Document Detail

Carotid artery rupture following radioiodine therapy for differentiated thyroid carcinoma.
MedLine Citation:
PMID:  22011859     Owner:  NLM     Status:  In-Data-Review    
INTRODUCTION: Radioiodine therapy for patients with differentiated thyroid cancer aims at reducing tumor recurrence by eradicating residual macro- and microscopic foci. Side effects are generally rare, tenuous and transient, with little clinical significance.
OBJECTIVE: To report a rare case of differentiated thyroid carcinoma presenting a large expansive solid mass at the base of the skull, with invasion of the left masticatory muscle and adjacent subcutaneous tissue, and without invasion of the carotid space, which evolved to carotid artery rupture following radioiodine therapy.
DISCUSSION: Side effects are uncommon after radioiodine therapy and when present, have mild intensity. Serious adverse events are very rare, especially those arising from structures not directly invaded by metastatic tissue with radioiodine uptake, as occurred in this case. This occurrence serves to raise awareness of the need for increased care when using radioiodine therapy on high-avidity masses located close to important structures.
Danilo da Silva Cunha; Maria Izilda Previato Simões; Dionísio Nepomuceno Viviani; Domingos Boldrini; Euclides Timóteo da Rocha; Sandra Regina Morini; Sonia Marta Moriguchi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arquivos brasileiros de endocrinologia e metabologia     Volume:  55     ISSN:  1677-9487     ISO Abbreviation:  Arq Bras Endocrinol Metabol     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-10-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0403437     Medline TA:  Arq Bras Endocrinol Metabol     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  419-25     Citation Subset:  IM    
Department Nuclear Medicine, Hospital de Câncer de Barretos, Barretos, SP, Brazil.
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