Document Detail

Carotid artery resection and reconstruction with expanded polytetrafluoroethylene for head and neck cancer.
MedLine Citation:
PMID:  18797418     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: There are controversies on management of carotid artery invasion in advanced head and neck cancer. En bloc resection has been considered a curative modality. In this study, we evaluated the feasibility of using expanded polytetrafluoroethylene (ePTFE) in reconstructing the common carotid artery in patients with carotid artery invasion requiring resection. METHOD: A retrospective study including 13 patients managed from 2002 to 2005. All patients underwent en bloc resection of the tumor and internal carotid artery then reconstructed with ePTFE. RESULTS: All patients had en bloc resection of the tumor together with internal carotid artery and reconstruction with ePTFE. Some patients required wound coverage with myocutaneous flaps in eight patients and local flaps in five patients. Intraoperative shunting was used in all patients. Intraoperative heparin infusion and postoperative low dose aspirin were used to prevent thrombosis. One patient developed graft blowout and he was treated with ligation without hemiplegia. One patient had minor stroke. The follow-up period was 18.4 +/- 8.6 months. No patient suffered from neurological deficit or graft occlusion. Disease survival was 61.5% in 1 year and 38.5% in 2 years. Overall survival was 18.3 months. CONCLUSION: En bloc resection and tumor together with carotid artery and ePTFE reconstruction is shown to be a feasible modality in treatment of advanced head and neck cancer with carotid artery invasion.
Beiping Miao; Yongtian Lu; Xinliang Pan; Dayu Liu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Laryngoscope     Volume:  118     ISSN:  1531-4995     ISO Abbreviation:  Laryngoscope     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-05     Completed Date:  2008-12-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2135-8     Citation Subset:  IM    
Department of Otolaryngology, Head and Neck Surgery, Qilu Hospital, Shandong University, Jinan, PR China.
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MeSH Terms
Blood Vessel Prosthesis Implantation*
Carcinoma, Squamous Cell / mortality,  pathology,  surgery*
Carotid Artery, Internal / pathology,  surgery*
Disease-Free Survival
Feasibility Studies
Follow-Up Studies
Middle Aged
Neoplasm Invasiveness
Neoplasm Recurrence, Local / mortality,  pathology,  surgery*
Neoplasm Staging
Otorhinolaryngologic Neoplasms / mortality,  pathology,  surgery*
Postoperative Complications / etiology,  mortality,  surgery
Prosthesis Failure
Prosthesis Fitting
Surgical Flaps
Reg. No./Substance:

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