Document Detail

Carotid arterial stiffness in patients with rheumatoid arthritis assessed by speckle tracking strain imaging: its association with carotid atherosclerosis.
MedLine Citation:
PMID:  22766304     Owner:  NLM     Status:  Publisher    
OBJECTIVES: Although a series of trials support the intima-media thickness (IMT) of carotid artery as a good predictor for the cardiovascular events in patients with rheumatoid arthritis (RA), the link between IMT, vascular elastic property and the disease activity of RA is not defined. We investigated the association between carotid atherosclerosis, elastic properties of the carotid arterial wall and clinical parameters of RA. METHODS: One hundred and twenty RA patients and fifty healthy controls were included. Peak systolic global circumferential and posterior radial strain of carotid artery were measured to assess the elastic properties. Beta stiffness index was used as conventional method for the distensibility of the carotid artery. RA activity was assessed by high sensitivity C-reactive protein (hsCRP) and disease activity score with 28 joints (DAS 28) and health assessment questionnaire (HAQ). RESULTS: Carotid plaques were more common in RA patients. RA patients with plaques were older and had an increased mean IMT, hsCRP, DAS 28, and longer disease duration compared with those without plaques. Peak systolic global circumferential and posterior radial strain were congruent with β stiffness index, and significantly lower in the RA group. Age, disease duration, hsCRP, DAS 28 showed significant correlations with mean IMT and parameters of carotid elastic property. CONCLUSIONS: Carotid atherosclerosis was more common in RA patients, and carotid arterial stiffness had significant correlation with disease duration and disease activity of RA. Speckle tracking strain imaging is a comparative method for the assessment of elastic properties of carotid artery of RA patients.
Ji Hyun Lee; Kyoung Im Cho; Seong Man Kim
Related Documents :
15919314 - The off-pump fontan procedure by simply cross-clamping the inferior caval vein.
8056404 - Surgery for tumor thrombi in the right atrium and inferior vena cava of patients with r...
18624114 - Three classes of pelvic and aortic lymphadenectomy in patients with cervical cancer.
12591684 - Congenital anomalies of the inferior vena cava revealed on ct in patients with deep vei...
20739064 - Relationship between individual cardiovascular risk factors and localization of coronar...
22286324 - Multislice coronary angiotomography in the assessment of coronary artery anomalous origin.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-5
Journal Detail:
Title:  Clinical and experimental rheumatology     Volume:  -     ISSN:  0392-856X     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8308521     Medline TA:  Clin Exp Rheumatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Division of Rheumatology, Department of Internal Medicine, 4-12, Daechung-dong, Jung-gu, Maryknoll Medical Center, Busan, Republic of Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  KLF4 and SOX9 transcription factors antagonize ?-catenin and inhibit TCF-activity in cancer cells.
Next Document:  Cervico-facial traumatic injuries at the Donka national hospital of the teaching hospital of Conakry...