Document Detail


Carotid Doppler microembolic signals in patients one year after heart valve surgery.
MedLine Citation:
PMID:  14714767     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Doppler ultrasound has been used to detect microemboli during and after cardiopulmonary bypass (CPB). The aim of the present study was to examine the frequency of microembolic signals (MES) in patients one year after heart valve replacement, to look for possible risk factors associated with MES and for any correlation with cerebral events. One hundred patients, 69 male and 31 female, mean age 66.3 +/- 12.4 years, were examined one year after heart valve replacement. Thirty patients, 61% male and 39% female, mean age 62.5 +/- 8.7 years, who had undergone cardiovascular operations without heart valve pathology served as controls. A newly developed microemboli detector, EMEX-25 (Hatteland Instrumentering, Norway) was used to detect MES from both carotid arteries. MES were detected in 61% of the valve patients. A correlation was found between the number of MES, previous cardiovascular operations, emergency surgery and EuroSCORE (p <0.05). There was no correlation between the number of MES and the level of anticoagulation expressed as international normalization ratio (INR), atrial fibrillation, serum-cholesterol, New York heart association (NYHA) class, gender, age, valve type or valve position. The average number of MES was not increased in seven patients who had experienced major (three) or minor (transient, four) cerebral events during follow-up. In the 30 nonvalve controls, MES were detected in 46% of the patients. MES were detected in valve patients as well as in nonvalve patients one year after surgery. In valve patients, a significant correlation was found between MES and previous surgery, emergency surgery and EuroSCORE. There was no correlation between the number of MES and INR level or postoperative cerebral events.
Authors:
Vadim Dalinin; Per Snorre Lingaas; Kjell Hatteland; Jan L Svennevig
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Perfusion     Volume:  18     ISSN:  0267-6591     ISO Abbreviation:  Perfusion     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2004-01-12     Completed Date:  2005-04-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8700166     Medline TA:  Perfusion     Country:  England    
Other Details:
Languages:  eng     Pagination:  333-7     Citation Subset:  IM    
Affiliation:
Department of Thoracic and Cardiovascular Surgery, Rikshospitalet, University of Oslo, Norway.
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MeSH Terms
Descriptor/Qualifier:
Aged
Carotid Artery Thrombosis / epidemiology,  etiology*,  ultrasonography
Cerebral Arteries / physiopathology,  ultrasonography
Female
Heart Valve Diseases / surgery,  ultrasonography
Heart Valve Prosthesis Implantation / adverse effects*,  statistics & numerical data
Humans
Male
Middle Aged
Risk Factors
Ultrasonography, Doppler / instrumentation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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