Document Detail


Carotid CT-angiography: low versus standard volume contrast media and low kV protocol for 128-slice MDCT.
MedLine Citation:
PMID:  21723684     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Availability and utilization of computed tomography angiography has been increasing recently. We aimed to assess the effectiveness of low amount of contrast media and low kV value in order to reduce possible side effects of contrast media and to provide optimization of kV value in the evaluation of the carotid artery with multi-detector computed tomography angiography. Forty one patients were randomized into two groups. Contrast media was administered at a dose of 1 ml/kg in group A patients and of 0.5 ml/kg in group B patients. kV value of 120 in group A and 100 in group B were chosen. Bolus tracking technique was used. Attenuation values of certain arterial segments were measured, and values over 200 HU were considered as significant. North American Symptomatic Carotid Endartherectomy Trial criteria were utilized in the evaluation of stenosis. Image quality in arterial segments of all cases was found to be sufficient for diagnosis. Arterial attenuation values were found to be higher in group B than group A. When compared separately in all arterial segments, there was no statistically significant difference between the groups. For stenosis, 615 arterial segments were evaluated. Moderate stenosis in eight segments and severe stenosis in three segments were identified in group A. Occlusion in three segments, severe stenosis in three segments, and moderate stenosis in 25 segments were detected in group B. Better image quality can be obtained, and the amount of contrast media can be reduced using low kV technique in carotid artery multi-detector computed tomography angiography examination.
Authors:
Mustafa Kayan; Mert Köroğlu; Ahmet Yeşildağ; Ergun Ceylan; Aykut Recep Aktaş; Selçuk Yasar; Giray Aynali; Cem Parlak; Mehmet Munduz; Cemil Gürses
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2011-07-01
Journal Detail:
Title:  European journal of radiology     Volume:  81     ISSN:  1872-7727     ISO Abbreviation:  Eur J Radiol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-10     Completed Date:  2013-01-14     Revised Date:  2013-04-26    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  2144-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Süleyman Demirel University, Faculty of Medicine, Dept. of Radiology, Isparta, Turkey. drkayan32@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Angiography / methods*
Carotid Arteries / radiography*
Carotid Artery Diseases / radiography*
Contrast Media / administration & dosage*
Dose-Response Relationship, Drug
Dose-Response Relationship, Radiation
Female
Humans
Iohexol / administration & dosage,  analogs & derivatives*,  diagnostic use
Male
Middle Aged
Radiation Dosage
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*
Chemical
Reg. No./Substance:
0/Contrast Media; 66108-95-0/Iohexol; 73334-07-3/iopromide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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