| Carotid artery stenting with proximal cerebral protection for patients with angiographic appearance of string sign. | |
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MedLine Citation:
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PMID: 20298988 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: The aim of this study was to assess the safety and effectiveness of carotid artery stenting (CAS) with proximal cerebral protection in patients showing string sign at carotid angiography. BACKGROUND: Presence of string sign is a well-known factor for adverse events in patients with severe carotid artery disease undergoing CAS. METHODS: We used retrospective analysis of a cohort of patients who underwent carotid angiography with the intention to undergo carotid stenting and had angiographically documented string sign in the target lesion. RESULTS: From October 2006 to August 2007, 25 patients (21 men and 4 women, mean age 70.9 +/- 8.7 years) presented with string sign during carotid angiography. This was 6.0% of a total of 416 patients studied during the time of the study. Twenty patients (80.0%) were symptomatic, and 5 (20.0%) were asymptomatic. Carotid artery stenting was performed successively in all patients. Proximal cerebral protection was applied in all but 1 patient. The 30-day death/stroke rate was 0%. At 12-month follow-up neurological events did not occur; 1 patient developed a nonfatal myocardial infarction, and another patient died from noncardiac cause. The 12-month death/stroke rate was 4.0%. CONCLUSIONS: Carotid stenting under proximal cerebral protection seems to be a feasible and safe procedure to manage patients with severe carotid stenosis in presence of angiographic string sign. Further prospective trials are required to prove efficacy of CAS in larger study populations. |
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Authors:
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Dimitrios N Nikas; Mohammed Abdel Ghany; Eugenio Stabile; Giovanni Sorropago; Salvatore Saccá; Luca Favero; Narek Zakaryan; Bernhard Reimers; Paulo Rubino |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: JACC. Cardiovascular interventions Volume: 3 ISSN: 1876-7605 ISO Abbreviation: JACC Cardiovasc Interv Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-19 Completed Date: 2010-06-17 Revised Date: 2012-08-29 |
Medline Journal Info:
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Nlm Unique ID: 101467004 Medline TA: JACC Cardiovasc Interv Country: United States |
Other Details:
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Languages: eng Pagination: 298-304 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Catheterization Laboratory, Cardiology Department, Mirano Public Hospital, Via Mariutto 13, Mirano (VE), Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Angioplasty, Balloon / adverse effects, instrumentation*, mortality Carotid Stenosis / complications, mortality, physiopathology, radiography*, therapy* Cerebrovascular Circulation* Feasibility Studies Female Humans Intracranial Embolism / etiology, mortality, physiopathology, prevention & control* Male Middle Aged Myocardial Infarction / etiology Patient Selection Retrospective Studies Risk Assessment Severity of Illness Index Stents* Stroke / etiology, mortality, physiopathology, prevention & control* Time Factors Treatment Outcome Ultrasonography, Doppler, Duplex |
| Comments/Corrections | |
Comment In:
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JACC Cardiovasc Interv. 2010 Mar;3(3):305-6
[PMID:
20298989
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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