Document Detail


Carotenoid intake does not mediate a relationship between reactive oxygen species and bright colouration: experimental test in a lizard.
MedLine Citation:
PMID:  18375850     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We performed experiments on male Australian painted dragon lizards (Ctenophorus pictus) to test the hypothesis that carotenoids can scavenge reactive oxygen species (ROS), protecting the organism from oxidative stress, and that this capacity is reflected in skin colours involved in signalling. Subsequent to 4 weeks of carotenoid treatment we used flow cytometry to analyse unspecified ROS (H(2)O(2), singlet oxygen, superoxide and peroxynitrite level), hereafter termed ROS, and baseline superoxide specifically (bSO in peripheral blood cells). Mean background levels of ROS and bSO did not differ between carotenoid-treated and control males. bSO, which represents the superoxide level in un-manipulated blood, was negatively correlated with colour development in all males, regardless of carotenoid treatment. Thus, carotenoid intake does not reduce circulating levels of ROS or bSO, suggesting that carotenoids are inefficient antioxidants in vivo and, therefore, are unlikely to provide a direct link between oxidative stress and colouration.
Authors:
Mats Olsson; Mark Wilson; Caroline Isaksson; Tobias Uller; Beth Mott
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of experimental biology     Volume:  211     ISSN:  0022-0949     ISO Abbreviation:  J. Exp. Biol.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-31     Completed Date:  2008-06-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243705     Medline TA:  J Exp Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1257-61     Citation Subset:  IM    
Affiliation:
School of Biological Sciences, The University of Wollongong, NSW 2522, Australia. molsson@uow.edu.au
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MeSH Terms
Descriptor/Qualifier:
Animals
Carotenoids / pharmacology*
Feeding Behavior / drug effects*
Female
Flow Cytometry
Lizards / physiology*
Male
Reactive Oxygen Species / metabolism*
Skin Pigmentation / drug effects*
Superoxides / metabolism
Chemical
Reg. No./Substance:
0/Reactive Oxygen Species; 11062-77-4/Superoxides; 36-88-4/Carotenoids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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