Document Detail

Carnitine in neonatal nutrition.
MedLine Citation:
PMID:  8576565     Owner:  NLM     Status:  MEDLINE    
Experimental evidence from several investigators suggests that carnitine is a conditionally essential nutrient for neonates. If carnitine is a conditionally essential nutrient for the neonate, most neonates on total parenteral nutrition in the United States are not receiving adequate nutritional support. The metabolic functions of carnitine are varied and important in several aspects of neonatal physiology. All neonates receiving breast milk receive dietary carnitine and most neonates receiving enteral infant formulas receive dietary carnitine at a level similar to that of the breast-fed neonate. However, most neonates on total parenteral nutrition receive no dietary carnitine. Investigators have been testing the working hypothesis that carnitine is a conditionally essential nutrient for the neonate for many years. This review discusses (1) data supporting the hypothesis, (2) reasons why it has not been either proved or disproved by now, and (3) the author's view of a prudent approach to dietary carnitine supplementation of neonates.
P R Borum
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of child neurology     Volume:  10 Suppl 2     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-03-13     Completed Date:  1996-03-13     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S25-31     Citation Subset:  IM    
Department of Food Science and Human Nutrition, University of Florida, Gainesville 32611-0370, USA.
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MeSH Terms
Age Factors
Animals, Newborn
Carnitine / metabolism*
Child Nutritional Physiological Phenomena
Infant, Newborn
Vitamin B Deficiency / metabolism*
Reg. No./Substance:

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