| Carnitine in neonatal nutrition. | |
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MedLine Citation:
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PMID: 8576565 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Experimental evidence from several investigators suggests that carnitine is a conditionally essential nutrient for neonates. If carnitine is a conditionally essential nutrient for the neonate, most neonates on total parenteral nutrition in the United States are not receiving adequate nutritional support. The metabolic functions of carnitine are varied and important in several aspects of neonatal physiology. All neonates receiving breast milk receive dietary carnitine and most neonates receiving enteral infant formulas receive dietary carnitine at a level similar to that of the breast-fed neonate. However, most neonates on total parenteral nutrition receive no dietary carnitine. Investigators have been testing the working hypothesis that carnitine is a conditionally essential nutrient for the neonate for many years. This review discusses (1) data supporting the hypothesis, (2) reasons why it has not been either proved or disproved by now, and (3) the author's view of a prudent approach to dietary carnitine supplementation of neonates. |
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Authors:
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P R Borum |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of child neurology Volume: 10 Suppl 2 ISSN: 0883-0738 ISO Abbreviation: J. Child Neurol. Publication Date: 1995 Nov |
Date Detail:
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Created Date: 1996-03-13 Completed Date: 1996-03-13 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 8606714 Medline TA: J Child Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: S25-31 Citation Subset: IM |
Affiliation:
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Department of Food Science and Human Nutrition, University of Florida, Gainesville 32611-0370, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Animals Animals, Newborn Carnitine / metabolism* Child Nutritional Physiological Phenomena Humans Infant, Newborn Vitamin B Deficiency / metabolism* |
| Chemical | |
Reg. No./Substance:
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541-15-1/Carnitine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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