Document Detail


Carl Friedrich Naumann and the introduction of enantio terminology: a review and analysis on the 150th anniversary.
MedLine Citation:
PMID:  17096375     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Enantiomorphism and enantiomorphous were the first enantio-based terms, introduced 150 years ago, by Carl Friedrich Naumann, a German crystallographer, to refer to non-superposable mirror-image crystals. The terminology was not adopted by Pasteur, the discoverer of molecular chirality, and was not embraced at first in the stereochemical context, until it was accepted in 1877 by Van't Hoff in the German edition of his proposal for the tetrahedral asymmetric carbon atom. In the 1890s the use of enantio terms began to spread in the research literature, and many new derivatives of Naumann's original two terms were subsequently introduced. Problems in the usage of some of the terms are often found in the literature, e.g., enantiomorphism is sometimes confused with chirality; enantiomeric is often misused; the meaning of some of the many derived terms, e.g., enantiosymmetric, enantioposition, etc., is unclear. All in all, Naumann should be remembered as the creator of essential terminology in the realm of chirality.
Authors:
Joseph Gal
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Publication Detail:
Type:  Biography; Historical Article; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Chirality     Volume:  19     ISSN:  0899-0042     ISO Abbreviation:  Chirality     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2006-12-27     Completed Date:  2007-10-11     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8914261     Medline TA:  Chirality     Country:  United States    
Other Details:
Languages:  eng     Pagination:  89-98     Citation Subset:  IM    
Copyright Information:
Copyright 2006 Wiley-Liss, Inc.
Affiliation:
Division of Clinical Pharmacology and Toxicology, University of Colorado School of Medicine, Denver, Colorado, USA. joe.gal@uchsc.edu
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MeSH Terms
Descriptor/Qualifier:
Chemistry, Analytic / history*
Crystallography / history
History, 18th Century
History, 19th Century
History, 20th Century
Stereoisomerism
Terminology as Topic*
Personal Name Subject
Personal Name Subject:
Carl Friedrich Naumann

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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