Document Detail


The caries environment: saliva, pellicle, diet, and hard tissue ultrastructure.
MedLine Citation:
PMID:  20630189     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The pathogenicity of the dental biofilm is modified by salivary and dietary factors, as well as by the characteristics of the tooth structure. The composition of the acquired pellicle can modify the mineral homeostasis of the tooth surfaces and the attachment of bacteria for the development of the biofilm. The substitution of sucrose from the diet by other less cariogenic sugars and/or sugar substitutes can contribute to reducing the pathogenicity of the biofilm. Saliva clears, dilutes, neutralizes, and buffers acids produced by the biofilm. In addition, saliva provides the biofilm/tooth structure with Ca(2+) PO(4)(3-) and F(-) ions, which can positively affect the equilibrium between demineralization-remineralization toward the remineralization and modify the susceptibility of the tooth structure to caries progression.
Authors:
Anderson T Hara; Domenick T Zero
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Dental clinics of North America     Volume:  54     ISSN:  1558-0512     ISO Abbreviation:  Dent. Clin. North Am.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-15     Completed Date:  2010-11-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0217440     Medline TA:  Dent Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  455-67     Citation Subset:  D; IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Affiliation:
Department of Preventive and Community Dentistry, Indiana University School of Dentistry, Indianapolis, IN 46202, USA. ahara@iupui.edu
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MeSH Terms
Descriptor/Qualifier:
Biofilms
Dental Caries / pathology,  physiopathology*
Dental Pellicle / microbiology,  physiology*
Diet, Cariogenic*
Humans
Mouth / microbiology,  physiology
Saliva / microbiology,  physiology*
Salivary Proteins and Peptides / physiology
Tooth / microbiology,  physiology*
Chemical
Reg. No./Substance:
0/Salivary Proteins and Peptides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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