Document Detail

Cardiovascular simulator improvement: pressure versus volume loop assessment.
MedLine Citation:
PMID:  21595711     Owner:  NLM     Status:  In-Data-Review    
This article presents improvement on a physical cardiovascular simulator (PCS) system. Intraventricular pressure versus intraventricular volume (PxV) loop was obtained to evaluate performance of a pulsatile chamber mimicking the human left ventricle. PxV loop shows heart contractility and is normally used to evaluate heart performance. In many heart diseases, the stroke volume decreases because of low heart contractility. This pathological situation must be simulated by the PCS in order to evaluate the assistance provided by a ventricular assist device (VAD). The PCS system is automatically controlled by a computer and is an auxiliary tool for VAD control strategies development. This PCS system is according to a Windkessel model where lumped parameters are used for cardiovascular system analysis. Peripheral resistance, arteries compliance, and fluid inertance are simulated. The simulator has an actuator with a roller screw and brushless direct current motor, and the stroke volume is regulated by the actuator displacement. Internal pressure and volume measurements are monitored to obtain the PxV loop. Left chamber internal pressure is directly obtained by pressure transducer; however, internal volume has been obtained indirectly by using a linear variable differential transformer, which senses the diaphragm displacement. Correlations between the internal volume and diaphragm position are made. LabVIEW integrates these signals and shows the pressure versus internal volume loop. The results that have been obtained from the PCS system show PxV loops at different ventricle elastances, making possible the simulation of pathological situations. A preliminary test with a pulsatile VAD attached to PCS system was made.
Jeison Fonseca; Aron Andrade; Denys E C Nicolosi; José F Biscegli; Juliana Leme; Daniel Legendre; Eduardo Bock; Julio Cesar Lucchi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Artificial organs     Volume:  35     ISSN:  1525-1594     ISO Abbreviation:  Artif Organs     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-05-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  454-8     Citation Subset:  IM    
Copyright Information:
© 2011, Copyright the Authors. Artificial Organs © 2011, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.
Department of Bioengineering, Institute Dante Pazzanese of Cardiology Department of Electronic and Computer Engineering, Technological Institute of Aeronautics, Marechal Eduardo Gomes, São José dos Campos Department of Electrical Engineering, University São Judas Tadeu, Taquari Department of Mechanical Engineering, University of São Paulo, "POLI", São Paulo Department of Mechanical Engineering, University of Campinas, Campinas, Brazil.
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