Document Detail


Cardiovascular risk in patients with chronic kidney diseases: a time for new risk markers?
MedLine Citation:
PMID:  17125066     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The number of patients with end-stage renal disease who need expensive dialysis treatment or transplantation is increasing all over the world. Therefore, new possibilities of prevention and treatment of chronic kidney diseases (CKD) are being looked for. However, patients with CKD represent a population not only at risk for progression to renal failure, but also at even greater risk for cardiovascular (CV) diseases. Extreme CV morbidity and mortality in dialysed patients is well-known, but recent studies stress a high CV risk even at early stage of CKD. Impaired renal function and/or albuminuria are now considered major CV risk factors. The reasons for this are not only a high prevalence of traditional CV risk factors in CKD patients or their insufficient treatment, but also the presence of non-traditional CV risk factors that could be specific for CKD. Some of these novel risk factors, particularly markers of inflammation, endothelial function, hemocoagulation and fibrinolysis are discussed, and their significance in the prediction of CV and renal outcome examined (Tab. 1, Ref 57).
Authors:
A Oksa
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Bratislavské lekárske listy     Volume:  107     ISSN:  0006-9248     ISO Abbreviation:  Bratisl Lek Listy     Publication Date:  2006  
Date Detail:
Created Date:  2006-11-27     Completed Date:  2007-02-13     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0065324     Medline TA:  Bratisl Lek Listy     Country:  Slovakia    
Other Details:
Languages:  eng     Pagination:  314-9     Citation Subset:  IM    
Affiliation:
Department of Clinical and Experimental Pharmacotherapy, Slovak Medical University, Bratislava, Slovakia. adrian.oksa@szu.sk
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MeSH Terms
Descriptor/Qualifier:
Biological Markers / analysis
Cardiovascular Diseases / diagnosis*,  etiology,  prevention & control
Chronic Disease
Disease Progression
Humans
Kidney Diseases / complications*,  diagnosis,  drug therapy
Risk Factors
Chemical
Reg. No./Substance:
0/Biological Markers
Comments/Corrections
Comment In:
Bratisl Lek Listy. 2007;108(4-5):169   [PMID:  17694798 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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