| Cardiovascular risk factors in polycystic ovary syndrome. | |
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MedLine Citation:
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PMID: 20455724 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A total of 31 women with polycystic ovary syndrome (PCOS) and 31 healthy age/body mass index matched controls were compared for serum hormones, basal and oral-glucose stimulated glucose, insulin, homocysteine, high sensitive C-reactive protein (hsCRP) and lipid levels. The women with PCOS had significantly higher serum fasting insulin, homocysteine, total cholesterol and LDL cholesterol level than controls, whereas no differences were detected in serum fasting or OGTT 60th- and 120th-minute glucose concentrations, hsCRP, HDL cholesterol, VLDL cholesterol and triglyceride levels between PCOS and control women. Insulin resistance was found in 54.8% (17/31) of PCOS patients by glucose: insulin (G/I) ratio, whereas only 29.0% (9/31) of control women (p = 0.04). Multivariate linear regression analysis revealed that only waist/hip ratio was independent determinants of G/I ratio. PCOS is associated with some biochemical and clinical risk factors for cardiovascular disease. Therefore, patients with PCOS should undergo comprehensive evaluation for recognised cardiovascular risk factors. |
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Authors:
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A Karaer; S Cavkaytar; I Mert; U Buyukkagnici; S Batioglu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology Volume: 30 ISSN: 1364-6893 ISO Abbreviation: J Obstet Gynaecol Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-11 Completed Date: 2010-08-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309140 Medline TA: J Obstet Gynaecol Country: England |
Other Details:
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Languages: eng Pagination: 387-92 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Dr Zekai Tahir Burak Woman Health Education and Research Hospital, Ankara, Turkey. drkaraer@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors Body Mass Index Cardiovascular Diseases / epidemiology* Case-Control Studies Female Humans Insulin Resistance Polycystic Ovary Syndrome / epidemiology* Prevalence Risk Factors Turkey / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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