| Cardiovascular risk factors in hemodialysis and peritoneal dialysis patients. | |
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MedLine Citation:
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PMID: 16509055 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Cardiovascular disease (CVD) is the major cause of mortality and morbidity of hemodialysis (HD) and peritoneal dialysis (CAPD) patients. We aimed to investigate the cardiovascular risk factors and their correlation with CVD in groups of HD and CAPD patients. METHODS: Thirty HD patients, 30 CAPD patients and 30 healthy controls were included in the study. Apolipoprotein A-l (apo A-l), apolipoprotein B (apo B), apolipoprotein(a) [Lp(a)] and high-sensitivity CRP (hs-CRP) were measured with a Beckman Coulter nephelometer, and homocysteine (Hcy) was determined with an Agilent HPLC analyzer. Lipid profile was determined with a Synchron LX 20 Pro analyzer. RESULTS: Hcy levels were 41.9+/-19.4, 41.8+/-38.5 and 9.3+/-3.5 micromol/L; Lp(a) levels were 325+/-315, 431+/-367 and 130+/-97 mg/L; hs-CRP levels were 3.78+/-3.21, 4.34+/-3.39 and 2.07+/-1.67 mg/L; apo A1/apo B ratios were 1.46+/-0.6, 1.36+/-0.5 and 1.80+/-0.59; total cholesterol levels were 3.56+/-0.7, 4.84+/-1.1 and 4.39+/-0.5 mmol/L; triglycerides were 1.44+/-0.5, 1.60+/-0.8 and 0.85+/-0.5 mmol/L in the HD, CAPD and control groups, respectively. CONCLUSION: HD and CAPD patients had higher Hcy, hs-CRP and Lp(a) levels and lower apo A/B ratios than controls. There was no significant difference between the HD and CAPD groups. Hypertension, age and hs-CRP showed a positive correlation with CVD. |
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Authors:
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F M Yilmaz; G Yilmaz; M Duranay; H Parpucu; M Senes; N Tekeli; D Y?cel |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Scandinavian journal of clinical and laboratory investigation Volume: 65 ISSN: 0036-5513 ISO Abbreviation: Scand. J. Clin. Lab. Invest. Publication Date: 2005 |
Date Detail:
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Created Date: 2006-03-01 Completed Date: 2006-03-07 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 0404375 Medline TA: Scand J Clin Lab Invest Country: Norway |
Other Details:
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Languages: eng Pagination: 739-45 Citation Subset: IM |
Affiliation:
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Clinical Biochemistry Laboratory, Ministry of Health, Ankara, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aging Apolipoproteins A / blood Apolipoproteins B / blood C-Reactive Protein / analysis Cardiovascular Diseases / blood*, complications*, etiology, mortality Case-Control Studies Female Homocysteine / blood, metabolism Humans Hypertension / blood, complications Kidney Diseases / blood, complications* Lipoprotein(a) / blood Male Peritoneal Dialysis* / adverse effects Renal Dialysis* / adverse effects Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Apolipoproteins A; 0/Apolipoproteins B; 0/Lipoprotein(a); 454-28-4/Homocysteine; 9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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