Document Detail


Cardiovascular risk factors in elderly normolipidemic acute myocardial infarct patients--a case controlled study from India.
MedLine Citation:
PMID:  19842447     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The goal of the present study was to address the various risk factors associated in normolipidemic acute myocardial infarction (AMI) patients admitted to the intensive coronary care unit (ICCU). The study compared serum lipid profiles, lipid peroxidation markers, antioxidants and inflammatory markers in acute myocardial infarction (AMI) patients and age/sex-matched controls. A lipid profile, lipid peroxidation, enzyme antioxidants, endogenous antioxidants, ischemia modified-albumin (IscMA), ceruloplasmin, C-reactive protein (CRP), fibrinogen, lipoprotein (a) and paraoxonase-1 activities were analyzed in 330 subjects, 165 acute myocardial infarction (AMI) patients and 165 age/sex-matched controls. We observed significantly higher (p < 0.0001) total cholesterol and triglyceride levels and lower high-density lipoprotein cholesterol (HDL-C) levels in the AMI patients. The lipoprotein (a), ceruloplasmin, CRP and fibrinogen levels were higher and the bilirubin, ascorbic acid, uric acid, albumin, superoxide dismutase, catalase, glutathione peroxidase and paraoxonase-1 activities were lower in AMI patients than controls. The malondialdehyde (MDA) and conjugated diene (CD) levels were significantly higher (p < 0.0001) in AMI patients.
Authors:
Arun Kumar; Suryakant Nagtilak; Ramiah Sivakanesan; Susil Gunasekera
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Southeast Asian journal of tropical medicine and public health     Volume:  40     ISSN:  0125-1562     ISO Abbreviation:  Southeast Asian J. Trop. Med. Public Health     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-10-21     Completed Date:  2009-11-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0266303     Medline TA:  Southeast Asian J Trop Med Public Health     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  581-92     Citation Subset:  IM    
Affiliation:
Department of Biochemistry Manipal College of Medical Sciences, Pokhara, Nepal. arun732003@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Case-Control Studies
Cholesterol, HDL / blood*
Cholesterol, LDL / blood
Female
Humans
India
Male
Middle Aged
Myocardial Infarction / blood*
Prospective Studies
Risk Factors
Triglycerides / blood*
Waist-Hip Ratio
Chemical
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Triglycerides

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