Document Detail

Cardiovascular risk factors and graded treadmill exercise endurance in healthy adults: The Framingham Offspring Study.
MedLine Citation:
PMID:  2913738     Owner:  NLM     Status:  MEDLINE    
To help describe the association between exercise endurance and cardiovascular risk factor profiles, 2,606 young and middle-aged healthy adults in the Framingham Offspring Study were given submaximal treadmill tests. For both men and women, exercise endurance was inversely related to resting heart rate (p less than 0.001), body mass index (p less than 0.001), systolic blood pressure (p less than 0.001) and blood glucose (p less than 0.01), and positively related to high density lipoprotein (HDL) cholesterol (p less than 0.05). In men, cigarette smoking (p less than 0.05), high levels of total cholesterol (p less than 0.01) and very low density lipoprotein (VLDL) cholesterol (p less than 0.001) were also associated with poor exercise endurance. After adjusting for age, resting heart rate and body mass index, significant independent associations persisted for HDL cholesterol (p less than 0.05) in both sexes and for systolic blood pressure, VLDL cholesterol, blood glucose and cigarette smoking in men (p less than 0.05). Risk factors associated with overt cardiovascular disease in older individuals are also associated with poor exercise endurance in those who are younger and asymptomatic.
R D Abbott; D Levy; W B Kannel; W P Castelli; P W Wilson; R J Garrison; J Stokes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  63     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1989 Feb 
Date Detail:
Created Date:  1989-03-06     Completed Date:  1989-03-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  342-6     Citation Subset:  AIM; IM    
Department of Medicine, University of Virginia School of Medicine, Charlottesville.
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MeSH Terms
Blood Glucose / analysis
Blood Pressure
Body Weight
Cardiovascular Diseases / etiology*
Cholesterol, HDL / blood
Exercise Test*
Heart Rate
Middle Aged
Physical Endurance*
Reference Values
Risk Factors
Time Factors
Reg. No./Substance:
0/Blood Glucose; 0/Cholesterol, HDL

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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