Document Detail

Cardiovascular responsiveness to vasoactive agents in rats with obstructive jaundice.
MedLine Citation:
PMID:  7166008     Owner:  NLM     Status:  MEDLINE    
1. Pressor responses to tyramine, beta-phenylethylamine and angiotensin II were normal in urethane-anaesthetized rats 7 days after division of the common bile duct. The pressor response to noradrenaline was enhanced at the highest dose level used. 2. The hypotensive response to haemorrhage was exaggerated in bile duct divided rats. 3. The exaggerated haemorrhagic hypotension of bile duct divided rats is unlikely to be the result of impaired vascular response to noradrenaline or angiotensin II, or of accumulation of false neurotransmitters by sympathetic nerves.
J P Finberg; R Seidman; O S Better
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental pharmacology & physiology     Volume:  9     ISSN:  0305-1870     ISO Abbreviation:  Clin. Exp. Pharmacol. Physiol.     Publication Date:    1982 Nov-Dec
Date Detail:
Created Date:  1983-05-05     Completed Date:  1983-05-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0425076     Medline TA:  Clin Exp Pharmacol Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  639-43     Citation Subset:  IM    
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MeSH Terms
Angiotensin II / pharmacology
Blood Pressure / drug effects
Cholestasis / physiopathology*
Hemodynamics / drug effects*
Hemorrhage / physiopathology
Norepinephrine / pharmacology
Phenethylamines / pharmacology
Tyramine / pharmacology
Vasoconstrictor Agents / pharmacology*
Reg. No./Substance:
0/Phenethylamines; 0/Vasoconstrictor Agents; 11128-99-7/Angiotensin II; 51-41-2/Norepinephrine; 51-67-2/Tyramine; 64-04-0/phenethylamine

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