Document Detail

Cardiovascular responses to tracheal extubation or LMA removal in normotensive and hypertensive patients.
MedLine Citation:
PMID:  9350368     Owner:  NLM     Status:  MEDLINE    
PURPOSE: This study was undertaken to evaluate the haemodynamic changes of tracheal extubation or removal of a laryngeal mask airway (LMA) in normotensive and hypertensive patients.
METHODS: In a randomized trial of normotensive and hypertensive patients (n = 40 of each), tracheal extubation or LMA removal was performed. Changes in heart rate (HR), mean arterial pressure (MAP) and rate-pressure product (RPP) were measured before and 1, 2, 3, 5, and 10 min after tracheal extubation or LMA removal.
RESULTS: In normotensive patients, HR, MAP and RPP increased following tracheal extubation or LMA removal, and remained elevated for a maximum three minutes (P < 0.05). In hypertensive patients, the haemodynamic increases in response to extubation or LMA removal were observed for up to five minutes (P < 0.05). The immediate cardiovascular responses to extubation were greater than those related to LMA removal in both normotensive and hypertensive patients (normotensive: HR; 95 +/- 14 vs 81 +/- 11, MAP; 124 +/- 18 vs 106 +/- 10, RPP; 14,951 +/- 2720 vs 10,654 +/- 1898, hypertensive: HR 105 +/- 10 vs 87 +/- 13, MAP; 146 +/- 17 vs 119 +/- 12, RPP; 20,492 +/- 1674 vs 12,862 +/- 2115, mean +/- SD, P < 0.05). Following extubation or LMA removal, these haemodynamic variables increased more markedly in hypertensive patients than in normotensive patients (P < 0.05).
CONCLUSION: Removal of LMA is associated with less cardiovascular change than tracheal extubation in both normotensive and hypertensive patients.
Y Fujii; H Toyooka; H Tanaka
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Retracted Publication    
Journal Detail:
Title:  Canadian journal of anaesthesia = Journal canadien d'anesthésie     Volume:  44     ISSN:  0832-610X     ISO Abbreviation:  Can J Anaesth     Publication Date:  1997 Oct 
Date Detail:
Created Date:  1997-12-04     Completed Date:  1997-12-04     Revised Date:  2013-11-27    
Medline Journal Info:
Nlm Unique ID:  8701709     Medline TA:  Can J Anaesth     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1082-6     Citation Subset:  IM    
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MeSH Terms
Blood Pressure / physiology
Heart Rate / physiology
Hemodynamics / physiology*
Hypertension / complications*,  physiopathology
Intraoperative Period
Intubation, Intratracheal / adverse effects*
Laryngeal Masks*
Middle Aged
Retraction In:
Can J Anaesth. 2013 Jun;60(6):619   [PMID:  23645568 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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