Document Detail


Cardiovascular responses to three simple, provocative tests of autonomic activity in sleeping infants.
MedLine Citation:
PMID:  11457766     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Whereas defective cardiovascular autonomic control has been implicated in the sudden infant death syndrome, relatively little is known about the normal development of autonomic control, due to the inability to measure blood pressure in infants noninvasively. We studied 12 normal infants [age: 13 +/- 2 (SD) wk] using a noninvasive method of continuous blood pressure recording and examined the cardiovascular responses to 45 degrees head-up tilting, a modified cold face test, and a loud noise. In head-up tilting, in both slow-wave sleep and rapid eye movement sleep, all infants displayed a rapid biphasic heart rate response (mean increase of 16% and mean decrease of 21%) and blood pressure response (mean increase of 16% and mean decrease of 16%), with a return to pretest values within 20 s. Both ice and noise caused a less pronounced biphasic response. In conclusion, at 3 mo, infants show the adult pattern of response to postural challenge. The short latency of the response suggests that neural inputs, apart from baroreceptors, are involved in the initial phase of the response.
Authors:
C Harrington; T Kirjavainen; A Teng; C E Sullivan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  91     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-07-17     Completed Date:  2001-09-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  561-8     Citation Subset:  IM    
Affiliation:
David Read Laboratory, University of Sydney, Sydney 2006, New South Wales, Australia. cth@med.usyd.edu.au
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation
Autonomic Nervous System / physiology*
Blood Pressure / physiology*
Blood Pressure Monitors
Diastole / physiology
Heart Rate / physiology*
Humans
Infant
Posture
Reference Values
Sleep / physiology*
Sleep Stages / physiology
Sleep, REM / physiology
Systole / physiology
Temperature
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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