Document Detail

Cardiovascular responses in hypertensive outpatients starting oral propranolol, determined from the brachial pulse upstroke.
MedLine Citation:
PMID:  7439235     Owner:  NLM     Status:  MEDLINE    
Simultaneous measurement of brachial artery pressures, systolic time intervals, initial pulse upstroke gradient and pulse rate was made in 7 adult hypertensive outpatients during rest supine and during bicycle ergometry at 2 different work rates. Measurements were repeated after 1, 6 and 13 wk on oral propranolol 80 mg thrice daily. Rise of pulse upstroke period (reversed after 1 wk) and of inflection time--analogous with preejection period--and fall of inflection, or diastolic, pressure (most marked at 1 wk) can be explained by early reduction of myocardial contractility and pulse rate. The fall of upstroke period, of peak, or systolic, pressure and of pulse rate (more marked after 1 wk) is related to a later 'adaptive' decrease in peripheral resistance. Much useful information can be obtained by such simple examination of the characteristics of the pulse wave in the brachial artery without complex, albeit noninvasive, cardiac investigations.
R Carlisle; A Porter; E B Raftery; I D Hill
Related Documents :
10750175 - A fatal case of gun blue ingestion in a toddler.
20517375 - Photoacoustic waves generated in blood studied using pulsed digital holography.
15743405 - Experimental and clinical study of the combined effect of arterial stiffness and heart ...
9205415 - Determination of appropriate recording force for non-invasive measurement of arterial p...
18838565 - Chronic actions of a novel oral b-type natriuretic peptide conjugate in normal dogs and...
17075205 - Does brachial pulse pressure predict coronary events?
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardiology     Volume:  12     ISSN:  0301-4711     ISO Abbreviation:  Eur J Cardiol     Publication Date:  1980  
Date Detail:
Created Date:  1981-02-19     Completed Date:  1981-02-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0404054     Medline TA:  Eur J Cardiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  63-72     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Administration, Oral
Blood Pressure / drug effects
Hemodynamics / drug effects
Hypertension / drug therapy*
Middle Aged
Myocardial Contraction / drug effects
Physical Exertion
Propranolol / pharmacology,  therapeutic use*
Pulse / drug effects*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Protective effect of Mercurascan after coronary artery ligation in the dog.
Next Document:  Ventricular wall thickness: a predictor of response to vasodilators in cardiomyopathy.