Document Detail

Cardiovascular and renal effects of hyperuricaemia and gout.
MedLine Citation:
PMID:  22303532     Owner:  NLM     Status:  In-Data-Review    
A number of epidemiological studies have reported an association between serum uric acid levels and a wide variety of high-risk conditions including hypertension, insulin resistance, and kidney and cerebro-cardiovascular disease. All things considered, serum uric acid may induce cardiovascular and kidney events both directly and indirectly by promoting other well-known mechanisms of damage. While asymptomatic hyperuricemia is currently not considered to be an indication for urate lowering therapy, there is growing evidence indicating a linear relationship between pharmacological reduction in serum uric acid and incidence of cardiovascular and renal events.
F Viazzi; G Leoncini; R Pontremoli
Publication Detail:
Type:  Journal Article     Date:  2012-01-19
Journal Detail:
Title:  Reumatismo     Volume:  63     ISSN:  0048-7449     ISO Abbreviation:  Reumatismo     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401302     Medline TA:  Reumatismo     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  253-62     Citation Subset:  IM    
University of Genoa.
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