| Cardiovascular reflexes in patients with malignant disease. | |
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MedLine Citation:
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PMID: 1592572 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although some authors have reported clinical features of autonomic dysfunction in patients with malignant disease only a few systematic studies have been carried out. We have investigated the autonomic function of 48 patients with carcinoma or lymphoma by testing their cardiovascular reflexes, and compared their results with those of 62 healthy volunteers. Our patients showed a smaller increase in heart rate and a greater fall in blood pressure on standing up, as well as a smaller rise in blood pressure in response to contralateral handgrip. The study group showed a higher percentage of established sympathetic lesion (54.2% vs 27.4%, p: 0.008) and of atypical pattern of global autonomic function impairment (50% vs 24.2%, p: 0.03) than the control group. Our data suggest that patients with malignant disease suffer from a definite autonomic dysfunction. |
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Authors:
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R Martin; J M Delgado; J M Moltò; J M Vicent; R Manzanares; R Insa; J Matìas-Guiu |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Italian journal of neurological sciences Volume: 13 ISSN: 0392-0461 ISO Abbreviation: Ital J Neurol Sci Publication Date: 1992 Mar |
Date Detail:
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Created Date: 1992-06-30 Completed Date: 1992-06-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006502 Medline TA: Ital J Neurol Sci Country: ITALY |
Other Details:
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Languages: eng Pagination: 125-9 Citation Subset: IM |
Affiliation:
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Neurological Department, Hospital Virgen de los Lirios, Alcoy, Spain. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Autonomic Nervous System / physiopathology* Female Heart Rate / physiology Hemodynamics / physiology* Humans Male Middle Aged Neoplasms / physiopathology* Reflex / physiology* Reflex, Stretch / physiology Valsalva Maneuver |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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