Document Detail

Cardiovascular reactivity to stress predicts future blood pressure status.
MedLine Citation:
PMID:  8406652     Owner:  NLM     Status:  MEDLINE    
Cardiovascular reactivity to stress may have a pathophysiological role in neurogenic hypertension. We studied the value of measuring blood pressure change during standardized mental and physical challenges to prediction of resting blood pressure status 6.5 years later among 206 middle-aged adults and their 164 children, with the latter group originally being tested while enrolled in elementary through high school. After adjustment for age, resting blood pressure, and body mass index at study entry, as well as length of follow-up, larger systolic and diastolic blood pressure responses to a combination of mental and physical challenges were associated with higher subsequent resting diastolic blood pressure 6.5 years later among adults. Among boys, but not among girls, larger systolic and diastolic blood pressure responses to challenge were associated with higher subsequent resting blood pressure. These data suggest that people who are at high risk for elevated blood pressure might have an exaggerated stress-induced cardiovascular response at a younger age.
K A Matthews; K L Woodall; M T Allen
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Hypertension     Volume:  22     ISSN:  0194-911X     ISO Abbreviation:  Hypertension     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1993-11-04     Completed Date:  1993-11-04     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7906255     Medline TA:  Hypertension     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  479-85     Citation Subset:  IM    
Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aging / physiology
Blood Pressure*
Cardiovascular System / physiopathology*
Hypertension / physiopathology
Physical Exertion
Prospective Studies
Sex Characteristics
Stress, Physiological / etiology,  physiopathology*
Stress, Psychological / physiopathology
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  In vivo hypothalamic release and synthesis of catecholamines in spontaneously hypertensive rats.
Next Document:  In vitro perfusion studies of resistance artery function in genetic hypertension.