Document Detail


Cardiovascular parameters after acute myocardial infarction and streptokinase administration in patients receiving coronary artery bypass grafts.
MedLine Citation:
PMID:  6391234     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 16 patients requiring coronary artery bypass grafting (10 control and 6 streptokinase patients), we compared the preoperative, operative, and postoperative cardiovascular parameters. Streptokinase patients had an acute myocardial infarction and attempted reperfusion with streptokinase before coronary artery bypass grafting. One patient failed to recannalize with streptokinase and one patient had reocclusion after withdrawal of heparin necessitating coronary artery bypass grafting. Examination of hemodynamic parameters revealed a lower preoperative mean blood pressure and an elevated pulmonary artery wedge pressure in streptokinase patients. The elevated pulmonary artery wedge pressure persisted through the postoperative period of observation. These results indicate that only minor differences exist between control and streptokinase patients. Emergency and elective coronary artery bypass grafting can be safely performed in patients treated with streptokinase for acute myocardial infarction without associated cardiogenic shock.
Authors:
L S Cook; S K Lucas; J E Cheatham; G D Myers; R G Johnson; L H Harrison; R C Elkins
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of surgery     Volume:  148     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-01-18     Completed Date:  1985-01-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  860-3     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Blood Pressure / drug effects
Clinical Trials as Topic
Coronary Artery Bypass*
Female
Hemodynamics / drug effects*
Humans
Male
Myocardial Infarction / drug therapy,  physiopathology*,  surgery
Prospective Studies
Pulmonary Wedge Pressure / drug effects
Streptokinase / therapeutic use*
Time Factors
Chemical
Reg. No./Substance:
EC 3.4.-/Streptokinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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