| Cardiovascular parameters after acute myocardial infarction and streptokinase administration in patients receiving coronary artery bypass grafts. | |
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MedLine Citation:
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PMID: 6391234 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In 16 patients requiring coronary artery bypass grafting (10 control and 6 streptokinase patients), we compared the preoperative, operative, and postoperative cardiovascular parameters. Streptokinase patients had an acute myocardial infarction and attempted reperfusion with streptokinase before coronary artery bypass grafting. One patient failed to recannalize with streptokinase and one patient had reocclusion after withdrawal of heparin necessitating coronary artery bypass grafting. Examination of hemodynamic parameters revealed a lower preoperative mean blood pressure and an elevated pulmonary artery wedge pressure in streptokinase patients. The elevated pulmonary artery wedge pressure persisted through the postoperative period of observation. These results indicate that only minor differences exist between control and streptokinase patients. Emergency and elective coronary artery bypass grafting can be safely performed in patients treated with streptokinase for acute myocardial infarction without associated cardiogenic shock. |
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Authors:
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L S Cook; S K Lucas; J E Cheatham; G D Myers; R G Johnson; L H Harrison; R C Elkins |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: American journal of surgery Volume: 148 ISSN: 0002-9610 ISO Abbreviation: Am. J. Surg. Publication Date: 1984 Dec |
Date Detail:
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Created Date: 1985-01-18 Completed Date: 1985-01-18 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370473 Medline TA: Am J Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 860-3 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Pressure
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drug effects Clinical Trials as Topic Coronary Artery Bypass* Female Hemodynamics / drug effects* Humans Male Myocardial Infarction / drug therapy, physiopathology*, surgery Prospective Studies Pulmonary Wedge Pressure / drug effects Streptokinase / therapeutic use* Time Factors |
| Chemical | |
Reg. No./Substance:
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EC 3.4.-/Streptokinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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