| Cardiovascular and metabolic complications during androgen deprivation: exercise as a potential countermeasure. | |
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MedLine Citation:
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PMID: 19488067 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Apart from the well-established adverse musculoskeletal and sexual health effects of androgen deprivation therapy (ADT), evidence is accumulating of substantial ADT-related cardiovascular and metabolic complications, which may impact quality of life and overall survival. In this brief review we discuss (1) the incidence of cardiovascular and metabolic complications during/following ADT from large cohort studies, (2) the increased risk factors for cardiovascular and metabolic disease from cross-sectional and prospective studies and (3) the use of physical exercise as a countermeasure in this new era of ADT-related toxicity. It is clear that exercise has the potential to provide a myriad of benefits to men undergoing ADT that may result in reduced morbidity and mortality, and subsequently improve quality of life. |
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Authors:
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D A Galvão; D R Taaffe; N Spry; D Joseph; R U Newton |
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Publication Detail:
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Type: Journal Article; Review Date: 2009-06-02 |
Journal Detail:
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Title: Prostate cancer and prostatic diseases Volume: 12 ISSN: 1476-5608 ISO Abbreviation: Prostate Cancer Prostatic Dis. Publication Date: 2009 |
Date Detail:
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Created Date: 2009-09-01 Completed Date: 2009-11-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9815755 Medline TA: Prostate Cancer Prostatic Dis Country: England |
Other Details:
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Languages: eng Pagination: 233-40 Citation Subset: IM |
Affiliation:
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Vario Health Institute, School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia. d.galvao@ecu.edu.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Androgen Antagonists
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adverse effects* Cardiovascular Diseases / etiology Exercise* Humans Male Metabolic Diseases / etiology Prostatic Neoplasms / drug therapy* Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Androgen Antagonists |
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