Document Detail


Cardiovascular and metabolic complications during androgen deprivation: exercise as a potential countermeasure.
MedLine Citation:
PMID:  19488067     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Apart from the well-established adverse musculoskeletal and sexual health effects of androgen deprivation therapy (ADT), evidence is accumulating of substantial ADT-related cardiovascular and metabolic complications, which may impact quality of life and overall survival. In this brief review we discuss (1) the incidence of cardiovascular and metabolic complications during/following ADT from large cohort studies, (2) the increased risk factors for cardiovascular and metabolic disease from cross-sectional and prospective studies and (3) the use of physical exercise as a countermeasure in this new era of ADT-related toxicity. It is clear that exercise has the potential to provide a myriad of benefits to men undergoing ADT that may result in reduced morbidity and mortality, and subsequently improve quality of life.
Authors:
D A Galvão; D R Taaffe; N Spry; D Joseph; R U Newton
Related Documents :
15649237 - Exercise-induced ventricular arrhythmias and cardiovascular death.
23415147 - Singer and listener perception of vocal warm-up.
2087577 - Cardiovascular complications of inactivity.
16375627 - The role of erythropoietin in myocardial protection: potential mechanisms and applicati...
17402237 - Relative toxicity of spent lubricant oil and detergent against benthic macro-invertebra...
6311607 - Increased prolyl 4-hydroxylase activity in the myocardium of endurance-trained mice.
Publication Detail:
Type:  Journal Article; Review     Date:  2009-06-02
Journal Detail:
Title:  Prostate cancer and prostatic diseases     Volume:  12     ISSN:  1476-5608     ISO Abbreviation:  Prostate Cancer Prostatic Dis.     Publication Date:  2009  
Date Detail:
Created Date:  2009-09-01     Completed Date:  2009-11-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815755     Medline TA:  Prostate Cancer Prostatic Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  233-40     Citation Subset:  IM    
Affiliation:
Vario Health Institute, School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia. d.galvao@ecu.edu.au
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Androgen Antagonists / adverse effects*
Cardiovascular Diseases / etiology
Exercise*
Humans
Male
Metabolic Diseases / etiology
Prostatic Neoplasms / drug therapy*
Risk Factors
Chemical
Reg. No./Substance:
0/Androgen Antagonists

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Impact of capsular incision on biochemical recurrence after radical perineal prostatectomy.
Next Document:  PTGS2-899G>C and prostate cancer risk: a population-based nested case-control study (ProtecT) and a ...