Document Detail


Cardiovascular and lymph flow changes caused by physiological hyperosmolar provocation in unanesthetized rats.
MedLine Citation:
PMID:  6698077     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cardiovascular and thoracic duct lymph (TDL) flow alterations were investigated in non-starved rats, lightly sedated with neuroleptanalgesia, before and after osmolar loading. 0.29-, 1.0- and 2.0-M xylose solutions were infused at the rate of 4 ml X h-1 for 20 min. Neither control animals receiving 0.29-M infusions (iso-osmolar) nor those which received 1- and 2-M infusions showed any detectable changes in cardiac output, heart rate, total peripheral resistance or any organ and tissue flow. On the other hand, TDL flow increased during the hyperosmolar infusions, giving a high degree of correlation with infusion time (r = 0.88 and 0.94, for 1- and 2-M infusions, respectively). These results indicate that hyperosmolar loading has only fluid physiological effects under normotensive conditions.
Authors:
G Quiros; J Ware
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes     Volume:  16     ISSN:  0014-312X     ISO Abbreviation:  Eur Surg Res     Publication Date:  1984  
Date Detail:
Created Date:  1984-04-20     Completed Date:  1984-04-20     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0174752     Medline TA:  Eur Surg Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  69-76     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure
Cardiac Output
Cardiovascular Physiological Phenomena*
Central Venous Pressure
Heart Rate
Infusions, Parenteral
Lymph / physiology*
Male
Osmolar Concentration*
Rats
Rats, Inbred Strains
Thoracic Duct
Vascular Resistance
Xylose / administration & dosage*
Chemical
Reg. No./Substance:
0/Xylose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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