Document Detail


Cardiovascular disease in Sub-Saharan Africa: a complex picture demanding a multifaceted response.
MedLine Citation:
PMID:  18607395     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A debate has emerged as to what should be the 'appropriate' cardiovascular agenda for sub-Saharan Africa. This Clinical Advance article reviews a recent study by Sliwa et al., which describes patients with newly diagnosed cardiovascular disease (CVD) presenting to a tertiary-care center in South Africa. The most common conditions among these patients were hypertension, heart failure, valvular heart disease, and coronary artery disease. Atherosclerotic risk factors were widely prevalent--only 13% of patients had no risk factors at all. Furthermore, a substantial proportion of patients presented at an advanced stage of disease. This study, which used state-of-the-art diagnostic technology, is an important addition to the growing database of information indicating that CVD in sub-Saharan Africa spans the spectrum from 'traditional', nonischemic etiologies to 'modern' diseases of lifestyle. The societal response to this diverse epidemiology should be similarly multifaceted. Moreover, efforts should be made to improve primary-care screening, early detection and treatment of CVD, and prompt referral of patients at early stages of disease.
Authors:
Rajesh Vedanthan; Valentin Fuster
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Publication Detail:
Type:  Journal Article     Date:  2008-07-08
Journal Detail:
Title:  Nature clinical practice. Cardiovascular medicine     Volume:  5     ISSN:  1743-4300     ISO Abbreviation:  -     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-22     Completed Date:  2008-10-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101226507     Medline TA:  Nat Clin Pract Cardiovasc Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  516-7     Citation Subset:  IM    
Affiliation:
Zena and Michael A Wiener Cardiovascular Institute, Mount Sinai Medical Center in New York, NY 10029, USA. rvedanthan@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Africa South of the Sahara / epidemiology
Atherosclerosis / complications,  epidemiology
Cardiovascular Diseases / diagnosis,  epidemiology*,  etiology,  therapy
Coronary Artery Disease / epidemiology
Developing Countries*
Disease Progression
Heart Failure / epidemiology
Heart Valve Diseases / epidemiology
Humans
Hypertension / epidemiology
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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