Document Detail


Cardiovascular consequences of the aging process.
MedLine Citation:
PMID:  10093764     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There are many challenges in the study of the normal age-associated changes that occur in the cardiovascular system, the most important of which is the fact that cardiovascular disease is so common in the elderly. In animal models and healthy humans, three age-associated changes with increasing age include (1) impaired left ventricular diastolic filling, (2) reduction in the adrenergic responsiveness to catecholamines, and (3) an increase in arterial stiffness. These changes likely are influenced by the increasingly sedentary lifestyle in the elderly. These age-associated changes also influence the manifestations of cardiovascular disease in the elderly and the response to therapy.
Authors:
S P Schulman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cardiology clinics     Volume:  17     ISSN:  0733-8651     ISO Abbreviation:  Cardiol Clin     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-05-17     Completed Date:  1999-05-17     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8300331     Medline TA:  Cardiol Clin     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  35-49, viii     Citation Subset:  IM    
Affiliation:
Coronary Care Unit, John Hopkins Hospital, Baltimore, Maryland, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aging / physiology*
Animals
Cardiovascular Diseases / epidemiology*,  physiopathology
Cardiovascular System / physiopathology*
Disease Models, Animal
Female
Humans
Life Style
Male
Models, Cardiovascular

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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