| Cardiovascular collapse associated with the use of methylmethacrylate. | |
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MedLine Citation:
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PMID: 8266779 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Methylmethacrylate has been used extensively in the United States since 1971 for the fixation of orthopedic prostheses. A chemical compound that generates a considerable amount of heat as it sets and hardens, it has been known to cause mild to moderate hypotension as well as cardiovascular collapse and death in some instances. Some of the purported etiologies of the untoward effects of methylmethacrylate include fat embolism, air embolism, bone marrow embolism, peripheral vasodilation, activation within the lungs of the clotting cascade, direct cardiovascular depressant effects of methylmethacrylate cement or monomer, and others. In this article, the use of methylmethacrylate in orthopedic procedures is reviewed, along with a discussion of some of the previously hypothesized causes of its side effects. Then a case report of its use in a 59-year-old woman with a pathological fracture of her left femur is presented. Finally, the implications for the anesthetist are noted, and suggested interventions to limit untoward effects with the use of methylmethacrylate are presented. |
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Authors:
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P W Pinto |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: AANA journal Volume: 61 ISSN: 0094-6354 ISO Abbreviation: AANA J Publication Date: 1993 Dec |
Date Detail:
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Created Date: 1994-01-27 Completed Date: 1994-01-27 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0431420 Medline TA: AANA J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 613-6 Citation Subset: N |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Femoral Fractures / surgery Fractures, Spontaneous / surgery Humans Intraoperative Complications / chemically induced*, nursing Methylmethacrylate Methylmethacrylates / adverse effects* Middle Aged Nurse Anesthetists Shock / chemically induced*, nursing |
| Chemical | |
Reg. No./Substance:
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0/Methylmethacrylates; 80-62-6/Methylmethacrylate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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