Document Detail

Cardiovascular changes after extraglottic airway insertion: a prospective, randomized comparison between the laryngeal mask or the new PAXpress.
MedLine Citation:
PMID:  15374554     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVE: To compare hemodynamic responses induced with the new extraglottic airway, PAXpress, and the classic Laryngeal Mask Airway (LMA). DESIGN: Prospective, randomized study. SETTING: Anesthesia department of a university teaching hospital. PATIENTS: 70 ASA physical status I and II patients, aged 18 to 65 years, scheduled to receive general anesthesia for extraabdominal procedures of short duration. INTERVENTIONS: Patients were randomly allocated to receive either a LMA (n = 35) or a PAXpress (n = 35) placement. After midazolam premedication (0.05 mg kg-1) and general anesthesia induction (propofol 2.5 mg kg-1, and fentanyl 1 microg kg-1) the airways were placed according to manufacturer instructions; then general anesthesia was maintained with a 2% sevoflurane concentration and an air/oxygen mixture. MEASUREMENTS AND MAIN RESULTS: Arterial blood pressure [both systolic (SBP) and diastolic (DBP)] and heart rate (HR) values were recorded immediately before airway placement, immediately after airway placement, then every 1 minute during the first 5 minutes. During the first 5 minutes after airway insertion, both SBP and DBP values were higher with the PAXpress than the LMA (repeated measures analysis of variance:p = 0.02 and p = 0.006, respectively), whereas no differences were reported in HR values. Also, the maximum percentage increase in both SBP and DBP values was larger with PAXpress [+19% (range: -19% to +80%) for SBP and +26% (range: -17% to +96%) for DBP] than the LMA [+9% (range: -30% to +90%) for SBP and +10% (range: -30% to +92%) for DBP] (p = 0.006 and p = 0.001, respectively). CONCLUSIONS: Although further studies are required to evaluate safety and airway trauma of this new extraglottic airway, placing the PAXpress produces more marked changes in hemodynamic variables as compared with those produced by the LMA.
Andrea Casati; Federico Vinciguerra; Emanuela Spreafico; Chiara Marchetti; Marta Putzu; Rossella Siliotti; Epifanio Mondello
Related Documents :
9483204 - Conicity index and waist-hip ratio and their relationship with total cholesterol and bl...
15470284 - Graded blood pressure reduction in hypertensive outpatients associated with use of a de...
17375994 - Prognostic value of admission blood pressure in traumatic brain injury: results from th...
9760344 - Magnitude and time course of hemodynamic responses to mueller maneuvers in patients wit...
1587414 - Corticosteroid treatment for inflammatory bowel disease in pediatric patients increases...
9789114 - Segmental differences in geometric, elastic and contractile characteristics of small in...
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of clinical anesthesia     Volume:  16     ISSN:  0952-8180     ISO Abbreviation:  J Clin Anesth     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-09-17     Completed Date:  2005-01-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8812166     Medline TA:  J Clin Anesth     Country:  United States    
Other Details:
Languages:  eng     Pagination:  342-6     Citation Subset:  IM    
Copyright Information:
Copyright 2004 Elsevier Inc.
Vita-Salute University of Milan-Department of Anesthesiology, IRCCS H. San Raffaele, Milan, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anesthesia, General*
Blood Pressure*
Heart Rate*
Intubation, Intratracheal / instrumentation*
Laryngeal Masks*
Middle Aged
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Adverse events associated with the intraoperative injection of isosulfan blue.
Next Document:  A noninvasive partial carbon dioxide rebreathing technique for measurement of pulmonary capillary bl...