| Cardiovascular birth defects and antenatal exposure to female sex hormones. | |
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MedLine Citation:
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PMID: 7151638 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The etiological correlations of congenital heart diseases to antenatal exposure of pregnant women to sex hormones were studied retrospectively. Of a total of 15,535 women who delivered between the years 1975-1977, 91 had babies with congenital heart disease (frequency 5.80/00). From these babies 11 were born to 559 mothers who had taken during pregnancy hormones of the estrogen-progesterone type (frequency 190/00). The remaining 80 babies were born to 14,976 mothers who had not taken such hormones (frequency 50/00). The main reason for having been given hormones were: bleeding of the first trimester in 80%, and the pregnancy test in 20%. Both groups of mothers had the same possibility for being affected by factors causing congenital heart diseases. An attempt is made to correlate the structure of the hormones given, the cause and time of the administration, the outcome of the newborn, and the type of heart disease. |
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Authors:
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E Hadjigeorgiou; A Malamitsi-Puchner; D Lolis; P Lazarides; D Nicolopoulos; D Kaskarelis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Developmental pharmacology and therapeutics Volume: 5 ISSN: 0379-8305 ISO Abbreviation: Dev Pharmacol Ther Publication Date: 1982 |
Date Detail:
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Created Date: 1983-03-11 Completed Date: 1983-03-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8003947 Medline TA: Dev Pharmacol Ther Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 61-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Estrogens
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adverse effects Female Gestational Age Gonadal Steroid Hormones / adverse effects* Heart Defects, Congenital / chemically induced* Humans Infant, Newborn Pregnancy Progesterone / adverse effects |
| Chemical | |
Reg. No./Substance:
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0/Estrogens; 0/Gonadal Steroid Hormones; 57-83-0/Progesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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