| Cardiovascular biomarkers in exhaled breath. | |
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MedLine Citation:
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PMID: 22824108 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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With each breath that we exhale, thousands of molecules are expelled in our breath, giving individuals a "breath-print" that can tell a lot about them and their state of health. Breath analysis is rapidly evolving as the new frontier in medical testing. The end of the 20th century and the beginning of the 21st century have arguably witnessed a revolution in our understanding of the constituents of exhaled breath and the development of the field of breath analysis and testing. Thanks to major breakthroughs in new technologies (infrared, electrochemical, chemiluminescence, and others) and the availability of mass spectrometers, the field of breath analysis has made considerable advances in the 21st century. Several methods are now in clinical use or nearly ready to enter that arena. Breath analysis has the potential to offer relatively inexpensive, rapid, noninvasive methods for detecting and/or monitoring a variety of diseases. Breath analysis also has applications in fields beyond medicine, including environmental monitoring, security, and others. This review will focus on exhaled breath as a potential source of biomarkers for medical applications with specific attention to applications (and potential applications) in cardiovascular disease. |
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Authors:
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Frank S Cikach; Raed A Dweik |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Progress in cardiovascular diseases Volume: 55 ISSN: 1873-1740 ISO Abbreviation: Prog Cardiovasc Dis Publication Date: 2012 Jul-Aug |
Date Detail:
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Created Date: 2012-07-24 Completed Date: 2012-10-03 Revised Date: 2013-05-02 |
Medline Journal Info:
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Nlm Unique ID: 0376442 Medline TA: Prog Cardiovasc Dis Country: United States |
Other Details:
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Languages: eng Pagination: 34-43 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Pathobiology/Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers
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analysis* Breath Tests* / methods Cardiovascular Diseases / diagnosis*, metabolism, physiopathology Exhalation* Humans Nitric Oxide / analysis Predictive Value of Tests Prognosis Volatile Organic Compounds / analysis |
| Grant Support | |
ID/Acronym/Agency:
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HL081064/HL/NHLBI NIH HHS; HL095181/HL/NHLBI NIH HHS; HL107147/HL/NHLBI NIH HHS; RR026231/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Volatile Organic Compounds; 10102-43-9/Nitric Oxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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