| Cardiovascular and biochemical responses to nebulised salbutamol in normal subjects. | |
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MedLine Citation:
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PMID: 6487508 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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When conventional therapeutic doses of nebulised salbutamol were given to normal volunteers, there was a significant rise in pulse rate, systolic blood pressure and plasma glucose and a significant fall in diastolic blood pressure and serum potassium in comparison with placebo. Such changes may be potentially hazardous in certain situations. Patients with airways obstruction due to chronic bronchitis who have coexistent ischaemic heart disease or diuretic induced hypokalaemia may be at particular risk from the unwanted cardiovascular and biochemical responses to nebulised salbutamol. |
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Authors:
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S R Smith; C Ryder; M J Kendall; R Holder |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: British journal of clinical pharmacology Volume: 18 ISSN: 0306-5251 ISO Abbreviation: Br J Clin Pharmacol Publication Date: 1984 Oct |
Date Detail:
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Created Date: 1984-12-20 Completed Date: 1984-12-20 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 7503323 Medline TA: Br J Clin Pharmacol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 641-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aerosols Albuterol / administration & dosage*, pharmacology Blood Glucose / analysis Blood Pressure / drug effects Cardiovascular System / drug effects* Female Humans Male Potassium / blood Pulse / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Aerosols; 0/Blood Glucose; 18559-94-9/Albuterol; 7440-09-7/Potassium |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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