Document Detail


Cardiovascular autonomic function in multiple sclerosis.
MedLine Citation:
PMID:  2708786     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The autonomic nervous function of the cardiovascular system was investigated by non-invasive methods in 30 multiple sclerosis patients between 20 and 50 years of age. The results were compared to those of 30 healthy controls in the same age group. Minor abnormalities of parasympathetic and sympathetic function occurred. Heart rate variation at deep breathing was reduced and more than half of the patients had abnormal responses during an orthostatic procedure, mainly as an increased rise in heart rate. Decreased rise in blood pressure at sustained handgrip was also demonstrated. The abnormalities correlated poorly with other clinical signs and symptoms in the patients.
Authors:
A M Nordenbo; F Boesen; E B Andersen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the autonomic nervous system     Volume:  26     ISSN:  0165-1838     ISO Abbreviation:  J. Auton. Nerv. Syst.     Publication Date:  1989 Feb 
Date Detail:
Created Date:  1989-05-26     Completed Date:  1989-05-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8003419     Medline TA:  J Auton Nerv Syst     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  77-84     Citation Subset:  IM    
Affiliation:
Department of Neurology, University Hospital, Rigshospitalet, Copenhagen, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Adult
Autonomic Nervous System / physiopathology*
Blood Pressure
Cardiovascular System / innervation,  physiopathology*
Female
Heart Rate
Humans
Male
Middle Aged
Multiple Sclerosis / physiopathology*
Parasympathetic Nervous System / physiopathology
Sympathetic Nervous System / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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