Document Detail


Cardiovascular autonomic dysfunction in patients with movement disorders.
MedLine Citation:
PMID:  18540148     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Autonomic dysfunction is common in parkinsonian syndromes, particularly those involving dysregulation of alpha-synuclein, and may result from neurodegeneration in autonomic regulatory regions of the brain or peripherial autonomic ganglia. The most limiting cardiovascular autonomic dysfunction in these diseases is orthostatic hypotension, which is particularly prominent in multiple system atrophy. Postprandial hypotension and supine hypertension, as well as dopaminergic therapy, often complicate the management of orthostatic hypotension in patients with parkinsonian syndromes.
Authors:
Benjamin L Walter
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cleveland Clinic journal of medicine     Volume:  75 Suppl 2     ISSN:  0891-1150     ISO Abbreviation:  Cleve Clin J Med     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-06-10     Completed Date:  2008-07-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8703441     Medline TA:  Cleve Clin J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S54-8     Citation Subset:  IM    
Affiliation:
Center for Neurological Restoration, Neurological Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA. walterb@ccf.org
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MeSH Terms
Descriptor/Qualifier:
Autonomic Nervous System / physiopathology*
Cardiovascular Diseases / diagnosis,  physiopathology*
Humans
Lewy Body Disease / physiopathology
Movement Disorders / diagnosis,  physiopathology*
Multiple System Atrophy / physiopathology
Parkinson Disease / physiopathology
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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