Document Detail

Cardiovascular alterations in severe pregnancy-induced hypertension seen with an intravenously given hydralazine bolus.
MedLine Citation:
PMID:  4035539     Owner:  NLM     Status:  MEDLINE    
The acute cardiovascular effects of a 10 milligram bolus of hydralazine was found to cause a significant increase in heart rate and cardiac index while decreasing mean arterial pressure and systemic vascular resistance index. A wide spectrum of individual responses was seen in terms of peak effects and duration of effects. The role of hydralazine in patients with severe pregnancy-induced hypertension was discussed and possible alternative therapy is suggested.
D B Cotton; B Gonik; K F Dorman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery, gynecology & obstetrics     Volume:  161     ISSN:  0039-6087     ISO Abbreviation:  Surg Gynecol Obstet     Publication Date:  1985 Sep 
Date Detail:
Created Date:  1985-10-03     Completed Date:  1985-10-03     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0101370     Medline TA:  Surg Gynecol Obstet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  240-4     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Pressure / drug effects
Cardiac Output / drug effects
Heart Rate / drug effects
Hydralazine / administration & dosage,  pharmacology,  therapeutic use*
Hypertension / drug therapy*
Pregnancy Complications, Cardiovascular / drug therapy*
Vascular Resistance / drug effects
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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