Document Detail


Cardiovascular adaptations to parabolic flight in rats: a radio-telemetry feasibility study.
MedLine Citation:
PMID:  11540693     Owner:  NASA     Status:  MEDLINE    
Abstract/OtherAbstract:
This experiment was a feasibility study which consisted in investigating arterial blood pressure and heart rate to transient and repeated exposure to microgravity in eight unrestrained rats previously implanted with radio-telemetry transmitter. The aim was to perform such recordings throughout all the phases of a parabola during parabolic flights. This study revealed that it was possible to collect the radio-signal without any interference with electronic or magnetic environment. We observed in microgravity a significant reduction in heart rate (6%) and a significant increase in arterial blood pressure (7%). In conclusion, such a study seems to be feasible during longer exposure to microgravity (space flight) in order to study the cardiovascular adaptation in rat.
Authors:
L Somody; S Fagette; J Frutoso; C Gharib; J P Blanquie; T Gharib; D Thierion; G Gauquelin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology     Volume:  4     ISSN:  1077-9248     ISO Abbreviation:  J Gravit Physiol     Publication Date:  1997 Jul 
Date Detail:
Created Date:  1998-08-22     Completed Date:  1998-08-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9437868     Medline TA:  J Gravit Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  P43-4     Citation Subset:  S    
Affiliation:
Laboratoire de Physiologie de l'Environnement, Faculte de Medecine, Lyon, France.
Space Flight Mission:
Flight Experiment; Parabolic Flight; manned; short duration
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological
Animals
Blood Pressure / physiology*
Cardiovascular Physiological Phenomena
Equipment Design
Feasibility Studies
Heart Rate / physiology*
Hypergravity
Male
Rats
Rats, Wistar
Space Flight / instrumentation*
Telemetry / instrumentation*
Weightlessness*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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