| Cardiovascular adaptations to parabolic flight in rats: a radio-telemetry feasibility study. | |
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MedLine Citation:
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PMID: 11540693 Owner: NASA Status: MEDLINE |
Abstract/OtherAbstract:
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This experiment was a feasibility study which consisted in investigating arterial blood pressure and heart rate to transient and repeated exposure to microgravity in eight unrestrained rats previously implanted with radio-telemetry transmitter. The aim was to perform such recordings throughout all the phases of a parabola during parabolic flights. This study revealed that it was possible to collect the radio-signal without any interference with electronic or magnetic environment. We observed in microgravity a significant reduction in heart rate (6%) and a significant increase in arterial blood pressure (7%). In conclusion, such a study seems to be feasible during longer exposure to microgravity (space flight) in order to study the cardiovascular adaptation in rat. |
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Authors:
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L Somody; S Fagette; J Frutoso; C Gharib; J P Blanquie; T Gharib; D Thierion; G Gauquelin |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology Volume: 4 ISSN: 1077-9248 ISO Abbreviation: J Gravit Physiol Publication Date: 1997 Jul |
Date Detail:
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Created Date: 1998-08-22 Completed Date: 1998-08-22 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9437868 Medline TA: J Gravit Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: P43-4 Citation Subset: S |
Affiliation:
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Laboratoire de Physiologie de l'Environnement, Faculte de Medecine, Lyon, France. |
Space Flight Mission:
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Flight Experiment; Parabolic Flight; manned; short duration |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Physiological Animals Blood Pressure / physiology* Cardiovascular Physiological Phenomena Equipment Design Feasibility Studies Heart Rate / physiology* Hypergravity Male Rats Rats, Wistar Space Flight / instrumentation* Telemetry / instrumentation* Weightlessness* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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