Document Detail


Cardiovascular actions of phenoxybenzamine.
MedLine Citation:
PMID:  19108145     Owner:  PIP     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Phenoxybenzamine increased the force of contraction and rate of the heart and lowered the blood pressure of dogs in pentobarbitone anaesthesia. This was preceded by depression of cardiac contractile force and a rise in blood pressure when phenoxybenzamine was injected following ganglion-blocking drugs or atropine. The positive inotropic and chronotropic and the hypertensive effects of phenoxybenzamine were prevented by pretreatment with reserpine or guanethidine.
Authors:
B G Benfey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of pharmacology and chemotherapy     Volume:  16     ISSN:  0366-0826     ISO Abbreviation:  Br J Pharmacol Chemother     Publication Date:  1961 Feb 
Date Detail:
Created Date:  2009-07-29     Completed Date:  2009-07-29     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0154627     Medline TA:  Br J Pharmacol Chemother     Country:  England    
Other Details:
Languages:  eng     Pagination:  6-14     Citation Subset:  -    
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