Document Detail

Cardiovascular actions of magnesium.
MedLine Citation:
PMID:  11219228     Owner:  NLM     Status:  MEDLINE    
Intracellular magnesium is an important modulator of calcium and potassium channels in cardiac myocytes. Hypomagnesemia is common in hospitalized patients and may contribute significantly to cardiac morbidity and mortality, particularly in states associated with myocardial ischemia. Therefore, it is important to maintain the plasma magnesium concentration within the normal range in asymptomatic patients and in patients with cardiac disease as prophylaxis against the occurrence of significant arrhythmias.
M S Agus; Z S Agus
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Critical care clinics     Volume:  17     ISSN:  0749-0704     ISO Abbreviation:  Crit Care Clin     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-02-21     Completed Date:  2001-04-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8507720     Medline TA:  Crit Care Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  175-86     Citation Subset:  IM    
Division of Pediatric Critical Care Medicine, MassGeneral Hospital for Children, Boston, Massachusetts, USA.
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MeSH Terms
Cardiovascular System / metabolism*
Guinea Pigs
Heart Diseases / drug therapy,  physiopathology
Intensive Care Units
Ion Channels / physiology
Magnesium / physiology*,  therapeutic use
Magnesium Deficiency / physiopathology
Myocardium / cytology,  metabolism*
Reg. No./Substance:
0/Ion Channels; 7439-95-4/Magnesium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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