Document Detail


Cardiovascular conditions and the evaluation of the heart in pregnancy-associated autopsies.
MedLine Citation:
PMID:  20629907     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Pregnancy-associated death is defined as the death of a woman from any cause during pregnancy or in the year after delivery. This review concentrates on cardiac conditions that may result in pregnancy-associated death including, but not limited to, acute myocardial infarction, endocarditis, peripartum cardiomyopathy, and prolonged QT syndrome. Lethal vascular conditions may also occur involving arterial dissection and thromboembolism, on occasion exacerbated by hypercoagulability, and altered hormonal and physiologic states. The autopsy evaluation of these patients includes a careful assessment of the medical history particularly for prior pregnancy-related conditions, fetal loss, and episodes of unexplained collapse. A family history of sudden death at an early age may be significant. At autopsy, evaluation for underlying syndromes such as Marfan, or evidence of intravenous narcotism should be undertaken. Autopsy examination involves careful dissection of the heart and vessels with consideration of conduction tract studies and possible genetic evaluation for prolonged QT syndrome.
Authors:
Jonathon Herbst; Calle Winskog; Roger W Byard
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of forensic sciences     Volume:  55     ISSN:  1556-4029     ISO Abbreviation:  J. Forensic Sci.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1528-33     Citation Subset:  IM    
Copyright Information:
© 2010 American Academy of Forensic Sciences.
Affiliation:
Forensic Science SA, 21 Divett Place, Adelaide, SA, 5000, Australia. herbst.jonathon@saugov.sa.gov.au
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