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Cardiovascular Complications in Children with HIV Infection.
MedLine Citation:
PMID:  21643782     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Before effective antiretroviral treatment was introduced in children with HIV, cardiovascular complications were a major cause of morbidity and mortality. Now that antiretroviral treatment is the standard of care in this population, there has been a shift from fulminant cardiovascular complications to recognition of cardiovascular issues related to HIV as a chronic disease state and its treatment. This review explores the recent advances in understanding the roles of atherosclerosis, inflammation, biomarkers, and metabolic abnormalities in cardiac function and cardiovascular disease risk in children with HIV. The true risk and prevalence of cardiovascular outcomes in HIV-infected children and adolescents has yet to be realized. Recently, however, investigators are exploring new cardiovascular health challenges that face children living with HIV, and developing strategies to lower the cardiovascular disease risk for these children.
Authors:
Amy Sims; Colleen Hadigan
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-4
Journal Detail:
Title:  Current HIV/AIDS reports     Volume:  -     ISSN:  1548-3576     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235661     Medline TA:  Curr HIV/AIDS Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Pediatric Cardiology, Children's National Medical Center, West Wing, Floor 3, 111 Michigan Avenue NW, Washington, DC, 20010, USA, asims@cnmc.org.
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