Document Detail


Cardiorespiratory responses during three repeated incremental exercise tests in sickle cell trait carriers.
MedLine Citation:
PMID:  17909842     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study investigated the cardioventilatory responses during heavy exercise in sickle cell trait carriers (SCTc) and subjects with normal hemoglobin (control group). Eight SCTc and six control subjects repeated three incremental exercise tests (Iet) separated by 10-min recoveries. Cardioventilatory parameters were analyzed at rest and during the first and third Iet. No significant difference in the ventilatory parameters [notably, maximal oxygen uptake (VO2max) and the ventilatory thresholds] was observed between the two groups. The time course of power output showed a significant difference between the first and third Iet from 80% of VO2max to VO2max (P < 0.05) in both groups. In conclusion, SCTc exhibited normal ventilatory responses during three successive Iet, which strongly suggests that this population, despite the presence of HbS in their red blood cells, is not limited during this type of aerobic exercise.
Authors:
Laurent Marlin; Philippe Connes; Sophie Antoine-Jonville; Julien Tripette; Mona Montout-Hedreville; Alain Sanouiller; Maryse Etienne-Julan; Olivier Hue
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-10-02
Journal Detail:
Title:  European journal of applied physiology     Volume:  102     ISSN:  1439-6327     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-11-16     Completed Date:  2009-02-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  181-7     Citation Subset:  IM    
Affiliation:
Laboratoire ACTES UPRES-EA 3596, UFR STAPS, Faculté des Sciences du Sport, Faculté de Médecine, Université des Antilles et de la Guyane, Campus de Fouillole, BP 592, 97159, Pointe-à-Pitre Cedex, Guadeloupe (FWI), France.
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MeSH Terms
Descriptor/Qualifier:
Anaerobic Threshold*
Exercise Test
Exercise Tolerance*
Female
Heart Rate*
Heterozygote
Humans
Lactic Acid* / blood
Male
Oxygen Consumption*
Physical Exertion*
Sickle Cell Trait / physiopathology*
Young Adult
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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