Document Detail

Cardiorespiratory response to feeding in newborn infants.
MedLine Citation:
PMID:  5964     Owner:  NLM     Status:  MEDLINE    
Milk feeds were given through indwelling nasogastric tubes to 14 infants with respiratory distress. Similar cardiorespiratory disturbances were observed when the infants were fed (5 ml/kg per feed) human milk, cow's mild, or distilled water. Pao2 fell after a feed but recovered to the prefeed value at 30 minutes, at which time Paco2 had fallen and the respiratory rate had increased. No changes in pH, heart rate, or blood pressure were observed. Portal sinus pressures rose after feeding in association with an increase in central venous pressure. In contrast, when the ill infants were fed human milk at a volume of 2-5 ml/kg per feed no consistent changes in any of the measurements were found. These studies suggested that the cardiorespiratory effects were related to volume displacement resulting from feeds being introduced into the stomach. The relation of the increase in central venous pressure and the magnitude and direction of shunting in infants with the respiratory distress syndrome is uncertain. Adverse effects may be avoided by giving smaller, and therefore even more frequent, feeds.
V Y Yu
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  51     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1976 Apr 
Date Detail:
Created Date:  1976-08-02     Completed Date:  1976-08-02     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  305-9     Citation Subset:  IM    
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MeSH Terms
Blood Pressure
Carbon Dioxide / blood
Cardiovascular System / physiopathology*
Enteral Nutrition / adverse effects*
Heart Rate
Hydrogen-Ion Concentration
Infant, Newborn
Milk, Human
Oxygen / blood
Partial Pressure
Respiratory Distress Syndrome, Newborn / physiopathology*
Time Factors
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7732-18-5/Water; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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