Document Detail


Cardiorespiratory function in Duchenne and Becker muscular dystrophy.
MedLine Citation:
PMID:  8827899     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to investigate the cardiorespiratory function in Duchenne (DMD) and Becker muscular dystrophy (BMO) patients and to determine whether there is a correlation between these functions and muscular strength. The study involved 32 patients with progressive muscular dystrophy (28 DMD and four BMD). The mean age of the patients was 9.6 +/- 3.5 years. Cardiac investigations were performed in all of the patients, and pulmonary function tests were obtained in 16 cases. In five cases (31%), vital capacity (VC) was less than 80 percent of the predicted value. There was a good correlation between VC and muscular strength. There were various cardiologic findings in 50 percent of the cases with DMD. Electrocardiographic changes were present in 43 percent of the patients. Left ventricular systolic function in the patients who could not walk was significantly lower than that of the patients who could walk. There may be some unknown mechanisms that preserve left ventricular function relatively in the normal range in spite of cardiac involvement.
Authors:
H A Taşdemir; E Cil; H Topaloğlu; K Yalaz; S Aysun; Y Renda; S Ozme
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Turkish journal of pediatrics     Volume:  38     ISSN:  0041-4301     ISO Abbreviation:  Turk. J. Pediatr.     Publication Date:    1996 Jul-Sep
Date Detail:
Created Date:  1996-11-20     Completed Date:  1996-11-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417505     Medline TA:  Turk J Pediatr     Country:  TURKEY    
Other Details:
Languages:  eng     Pagination:  307-14     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Hacettepe University Faculty of Medicine.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Child, Preschool
Echocardiography
Electrocardiography
Heart Diseases / etiology*
Humans
Male
Muscular Dystrophies / complications*,  physiopathology
Respiration Disorders / etiology*
Respiratory Function Tests
Ventricular Function, Left

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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