Document Detail


Cardiorespiratory fitness modifies the association between dietary fat intake and plasma fatty acids.
MedLine Citation:
PMID:  12821879     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To investigate the relation between (1) cardiorespiratory fitness and plasma saturated, monounsaturated and polyunsaturated fatty acids and (2) the interactions between cardiorespiratory fitness, dietary fat intake and plasma fatty acid composition. DESIGN: Cross-sectional analysis. SETTING AND SUBJECTS: The subjects were randomly selected, 127 middle-aged Finnish men participating in the DNASCO exercise intervention study. INTERVENTIONS: Cardiorespiratory fitness was determined spiroergometrically, dietary intake of macro- and micronutrients by 4-day food records and plasma fatty acids by gas chromatography. The subjects were divided into tertiles of aerobic fitness. RESULTS: Differences between fitness tertiles were not observed for dietary intake of total fat, and saturated, monounsaturated or polyunsaturated fatty acids (percent of total energy). In contrast, plasma saturated fatty acids were significantly lower (P <0.01) and polyunsaturated fatty acids significantly higher (P <0.05) in the highest fitness tertile compared to the lowest tertile. Dietary saturated fat intake was positively associated with plasma saturated fatty acids (r=0.342; P <0.05) and inversely with plasma polyunsaturated fatty acids (r=-0.453; P <0.01) only in the lowest fitness tertile. In addition, a positive correlation between body mass index and plasma saturated fatty acids (r=0.516; P <0.01) as well as a negative correlation between body mass index and plasma polyunsaturated fatty acids (r=-0.516; P <0.01) was observed in the lowest tertile solely. CONCLUSION: Different levels in cardiorespiratory fitness are associated with different levels in plasma saturated and polyunsaturated fatty acids and lead to modifications in the association between dietary and plasma fatty acids. These findings can perhaps be explained by a reduced hepatic fatty acid and lipoprotein synthesis as well as by an enhanced muscular lipid utilization, which are commonly seen in those who are physically active and who exhibit a higher level of fitness.
Authors:
D König; S B Väisänen; C Bouchard; M Halle; T A Lakka; M W Baumstark; M Alen; A Berg; R Rauramaa
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  57     ISSN:  0954-3007     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-06-24     Completed Date:  2003-12-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  810-5     Citation Subset:  IM    
Affiliation:
Department of Prevention, Rehabilitation and Sports Medicine, Center for Internal Medicine, University Hospital, Hugstetter Strasse 55, D-79106 Freiburg im Breisgau, Germany. Dani@msml.ukl.uni-freiburg.de
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MeSH Terms
Descriptor/Qualifier:
Chromatography, Gas
Cohort Studies
Cross-Sectional Studies
Diet Records
Dietary Fats / administration & dosage*,  metabolism
Fatty Acids / analysis,  blood*
Fatty Acids, Monounsaturated / analysis,  blood
Fatty Acids, Unsaturated / analysis,  blood*
Humans
Male
Middle Aged
Physical Fitness / physiology*
Spirometry
Chemical
Reg. No./Substance:
0/Dietary Fats; 0/Fatty Acids; 0/Fatty Acids, Monounsaturated; 0/Fatty Acids, Unsaturated

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