Document Detail

Cardiorespiratory exercise tolerance in asymptomatic children with Ebstein's anomaly.
MedLine Citation:
PMID:  10089242     Owner:  NLM     Status:  MEDLINE    
The aim of the study was to evaluate cardiorespiratory exercise tolerance in asymptomatic children with Ebstein's anomaly. Eleven children with a mean age of 9.6 years were prospectively studied by spirometry, cardiopulmonary exercise testing (bicycle ergometer n = 8, treadmill test n = 3), and contrast echocardiography. A right-to-left atrial shunt was detected by contrast echocardiography in 7 children (group 1), whereas no shunt was found in 4 (group 2). VO2 max was decreased [84.5 (SD = 16.8)] and was strongly correlated to oxygen saturation in group 1 (p < 0.0001). Oxygen saturation at peak uptake was significantly decreased compared to baseline [97.4 (SD = 2.0) vs 90% (SD = 9.5%), p = 0.02] and was significantly lower in group 1 than in group 2 [85.7 (2.2) vs 98.2% (SD = 1.2%), p = 0. 03]. Oxygen desaturation was related to a right-to-left atrial shunt (p = 0.01). Decreased VO2 max was also correlated to the small size of the left ventricle (p = 0.05). We concluded that decreased exercise tolerance in children with asymptomatic Ebstein's anomaly is related to a right-to-left atrial shunt and to a small left ventricle. In case of poor exercise tolerance, a contrast echocardiography should be performed to detect an atrial septal defect.
J M Lupoglazoff; I Denjoy; M Kabaker; K Benali; B Riescher; S Magnier; C Gaultier; A Casasoprana
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  20     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:    1999 May-Jun
Date Detail:
Created Date:  1999-04-20     Completed Date:  1999-04-20     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  189-94     Citation Subset:  IM    
Department of Pediatric Cardiology, Robert Debré Hospital 48, Boulevard Sérurier, 75019 Paris, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Ebstein Anomaly / physiopathology*,  ultrasonography
Echocardiography, Doppler, Color
Exercise Test
Exercise Tolerance* / physiology
Follow-Up Studies
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Elevation of cardiac troponin I in the acute stage of Kawasaki disease.
Next Document:  Spontaneous closure of atrial septal defects.