Document Detail

Cardiorespiratory changes during upper gastrointestinal endoscopy.
MedLine Citation:
PMID:  17594289     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To determine the changes in oxygen saturation, blood pressure and heart rate during various endoscopic procedures and to find out the risk factors for these changes.
METHODS: Forty patients without cardiorespiratory disorders were recruited. Oxygen saturation, blood pressure and pulse rate were monitored during endoscopy using pulse oximeter and automated blood pressure monitor. These were recorded from baseline until 5 minutes after the procedure. The important variables, which were evaluated in relation to these changes, included age, gender, duration of the procedure and drug/dosages.
RESULTS: Baseline mean oxygen saturation was 96.8 +/- 1.55%. It decreased significantly to 94.53 +/- 3.30%(p= 0.002) during insertion of probe. Mild to moderate hypoxia was found in 19 (47.5%) patients. Severe hypoxia was found in 5 (12.5%) patients. The variables that reached statistical significance for desaturation were age greater than 50 years and duration longer than 27 minutes. Changes in pulse rate were significant post-sedation, during probe insertion, during scoping, at removal of probe and immediately post-procedure (p < 0.02). The mean change in systolic blood pressure was not significant throughout the procedure when compared to baseline, however 14 (35%) patients developed transient hypertension.
CONCLUSIONS: Mild to moderate hypoxia is common during endoscopic procedures and of no serious consequence. However severe hypoxia is less common. We recommend a non-invasive monitoring in patients with age greater than 50 years and procedure longer than 27 minutes.
B B Osinaike; A Akere; T O Olajumoke; E O Oyebamiji
Related Documents :
6122539 - Total and hindlimb o2 uptake and blood flow in hypoxic dogs given dopamine.
6323659 - The effects of hypobaric hypoxia on the corticotroph population of the adenohypophysis ...
8908229 - Metabolic, ventilatory and circulatory effects of doxapram in anaesthetized pigs during...
179279 - Mitochondrial cytochrome concentrations in rat heart and liver as a consequence of diff...
1248989 - Sustained venoconstriction in man supplemented with co2 at high altitude.
20142529 - Ventilatory and cardiovascular responses to hypercapnia and hypoxia in multiple-system ...
6574879 - The effect of ventilation on the accuracy of pulmonary artery and wedge pressure measur...
22217879 - Blood pressure stability in hemodialysis patients confers a survival advantage: results...
1432309 - First- and third-order models for determining arterial compliance.
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  African health sciences     Volume:  7     ISSN:  1729-0503     ISO Abbreviation:  Afr Health Sci     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-06-27     Completed Date:  2008-11-24     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  101149451     Medline TA:  Afr Health Sci     Country:  Uganda    
Other Details:
Languages:  eng     Pagination:  115-9     Citation Subset:  IM    
Department of Anaesthesia, LAUTECH Teaching Hospital, Osogbo, Osun State, Nigeria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anoxia / etiology
Blood Pressure
Endoscopy, Gastrointestinal / adverse effects*
Heart Rate
Middle Aged
Monitoring, Physiologic*
Oxygen Consumption
Risk Factors
Upper Gastrointestinal Tract / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Neonatal nutrition and later outcomes of very low birth weight infants at Kenyatta National Hospital...
Next Document:  Family Medicine may be helpful in improving health care delivery in sub-Saharan Africa.