Document Detail


Cardiorespiratory adaptations during the six-minute walk test in chronic heart failure patients.
MedLine Citation:
PMID:  15187823     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The six-minute walk test (6-MWT) is widely used to assess exercise tolerance in chronic heart failure patients (CHF). The aim of this study was to analyse cardiorespiratory parameters kinetics during the 6-MWT in CHF and in healthy subjects. METHODS: A treadmill, symptom-limited exercise test and a 6-MWT were performed by 14 CHF under optimal drug treatment (CHFD), 17 CHF with cardiac resynchronization (CHFP), and 12 healthy subjects. Cardiorespiratory responses were assessed by a validated portable system. RESULTS: All subjects exceeded their ventilatory threshold during the 6-MWT. Healthy subjects and CHF performed the 6-MWT around 75 and 90% of peak oxygen uptake (V'O2) respectively (P<0.001). In CHF, a steady state was observed only for walking speed and V'O2, with a slight delay in comparison with healthy subjects, for whom a steady state was also observed for carbon dioxide production and ventilation (V'E). During the 6-MWT, the V'E adaptation was due mainly to an increase in tidal volume (VT) in CHFD, whereas in CHFP, it was due to a similar increase in VT and breathing frequency (f). In these patients, the 6-MWT VT/f slope was lower than in CHFD (P<0.01). CONCLUSIONS: During the 6-MWT, the V'O2 steady state is slightly delayed in CHF, which could be related partly to their higher exercise intensity. Moreover, each CHF group is characterized by a specific ventilation components response during the 6-MWT.
Authors:
Gaëlle Kervio; Nathalie S Ville; Christophe Leclercq; Jean-Claude Daubert; François Carre
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology     Volume:  11     ISSN:  1741-8267     ISO Abbreviation:  Eur J Cardiovasc Prev Rehabil     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-06-09     Completed Date:  2004-09-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101192000     Medline TA:  Eur J Cardiovasc Prev Rehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  171-7     Citation Subset:  IM    
Affiliation:
Groupe de Recherche Cardiovasculaire, Université de Rennes, France. gaelle.kervio@club-internet.fr
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological / physiology*
Aged
Carbon Dioxide / metabolism
Cardiovascular System / physiopathology*
Exercise Test
Female
Heart Failure / physiopathology*
Heart Rate
Humans
Kinetics
Male
Middle Aged
Oxygen Consumption
Pulmonary Ventilation
Respiratory System / physiopathology*
Tidal Volume
Time Factors
Walking / physiology*
Chemical
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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