Document Detail

Cardiopulmonary performance during exercise in patients with repaired tetralogy of Fallot with absent pulmonary valve.
MedLine Citation:
PMID:  7617505     Owner:  NLM     Status:  MEDLINE    
In patients with tetralogy of Fallot and absent pulmonary valve, the dilated pulmonary arteries sometimes result in bronchial compression and pulmonary symptoms due to airway obstruction, recurrent pulmonary infection, and development of bronchiectasis. After complete intracardiac repair, residual pulmonary disease may be expected to result in impaired cardiopulmonary performance during exercise. To assess this hypothesis, nine patients with tetralogy of Fallot and absent pulmonary valve underwent exercise testing and were compared to 38 patients with tetralogy of Fallot repaired using a transannular patch. All patients were exercised to maximum volition using a 1 minute incremental treadmill protocol with monitoring of pulmonary functions and expired gases. Maximal heart rate, maximal oxygen consumption, oxygen consumption at anaerobic threshold, and maximal respiratory exchange ratio were similar for the two groups. There was no significant difference for ventilation and gas exchange parameters at rest or at maximal exercise, and values for both groups were below the predicted normal for healthy subjects. Breathing reserve, however, did tend to be somewhat lower in the group with tetralogy of Fallot with absent pulmonary valve. In summary, despite significant preoperative symptoms, cardiopulmonary performance during exercise in patients with tetralogy of Fallot and absent pulmonary valve is similar to patients with tetralogy of Fallot repaired with a transannular patch.
N Mulla; S M Paridon; W W Pinsky
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  16     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:    1995 May-Jun
Date Detail:
Created Date:  1995-08-18     Completed Date:  1995-08-18     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  120-6     Citation Subset:  IM    
Division of Cardiology, Children's Hospital of Michigan, Detroit 48201, USA.
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MeSH Terms
Cardiovascular Physiological Phenomena*
Child, Preschool
Exercise Test*
Heart Rate
Lung / physiology*
Oxygen Consumption
Pulmonary Gas Exchange
Pulmonary Valve* / surgery
Respiratory Function Tests
Tetralogy of Fallot / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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