Document Detail

Cardiopulmonary parameters and prognosis after severe multiple trauma.
MedLine Citation:
PMID:  448765     Owner:  NLM     Status:  MEDLINE    
Comprehensive cardiopulmonary and metabolic monitoring of severely traumatized patients for 7 days from the time of injury has allowed us to determine parematers which correlate with survival and nonsurvival. The earliest and most persistent change is an increased pulmonary vascular resistance which results in right heart overload and failure. Left heart "failure" which has been previously described with acute respiratory failure and shock is shown to be a mathematical artifact caused by dilatation of the right heart and encroachment on left ventricular filling volume. Causes of death in most patients were not directly referable to right heart dysfunction but we postulate that hypercoagulability and microembolism could independently produce the observed pulmonary vascular changes as well as the multiple organ failure which usually was responsible for death. Resolution of this question will require more sophisticated hematologic evaluation.
J A Stürm; F R Lewis; O Trentz; H J Oestern; G Hempelman; H Tscherne
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of trauma     Volume:  19     ISSN:  0022-5282     ISO Abbreviation:  J Trauma     Publication Date:  1979 May 
Date Detail:
Created Date:  1979-08-29     Completed Date:  1979-08-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376373     Medline TA:  J Trauma     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  305-18     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Coagulation
Blood Gas Analysis
Blood Pressure
Cardiac Output
Central Venous Pressure
Heart / physiopathology*
Heart Rate
Middle Aged
Pulmonary Circulation
Time Factors
Vascular Resistance
Wounds, Nonpenetrating / mortality,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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